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由单核细胞增生李斯特菌菌血症引起的腰大肌脓肿合并主动脉内移植物感染:一例报告及文献综述(CARE 病例报告)

Psoas abscess associated with aortic endograft infection caused by bacteremia of Listeria monocytogenes: A case report and literature review (CARE Complaint).

作者信息

Ma Jen-Wen, Hu Sung-Yuan, Lin Tzu-Chieh, Tsai Che-An

机构信息

Department of Emergency Medicine, Taichung Veterans General Hospital.

School of Medicine.

出版信息

Medicine (Baltimore). 2019 Nov;98(45):e17885. doi: 10.1097/MD.0000000000017885.

Abstract

RATIONALE

Endograft infection following endovascular stent for aortic aneurysm is rare (0.6%-3%), but it results in high mortality rate of 25% to 88%.

PATIENT CONCERNS

A 66-year-old hypertensive man underwent an endovascular stent graft for abdominal aortic aneurysm 18 months ago. Recurrent episodes of fever, chills, and abdominal fullness occurred 6 months ago before this admission. Laboratory data showed 20 mg/dL of C-reactive protein and abdominal computed tomography (CT) revealed an aortic endoleak at an urban hospital, so 4-day course of intravenous (IV) amoxicillin/clavulanic acid was given and he was discharged after fever subsided. He was admitted to our hospital due to fever, chills, and watery diarrhea for 1 day. Abdominal CT showed left psoas abscess associated with endograft infection. Blood culture grew Listeria monocytogenes.

DIAGNOSIS

Left psoas abscess associated with endograft infection caused by bacteremia of Listeria monocytogenes.

INTERVENTIONS

IV ampicillin with 8 days of synergistic gentamicin was prescribed and it created satisfactory response. Ampicillin was continued for 30 days and then shifted to IV co-trimoxazole for 12 days.

OUTCOMES

He remained asymptomatic with a decline of CRP to 0.36 mg/dL and ESR to 39 mm/h. He was discharged on the 44th hospital day. Orally SMX/TMP was prescribed for 13.5 months.

LESSONS

Only few cases of aortic endograft infection caused by Listeria monocytogenes had been reported. In selected cases, particularly with smoldering presentations and high operative risk, endograft retention with a prolonged antimicrobial therapy seem plausible as an initial therapeutic option, complemented with percutaneous drainage or surgical debridement if necessary.

摘要

原理

血管内支架治疗主动脉瘤后发生移植物感染很罕见(0.6%-3%),但其导致的死亡率高达25%至88%。

患者情况

一名66岁的高血压男性18个月前接受了腹主动脉瘤血管内支架植入术。此次入院前6个月出现反复发热、寒战和腹部胀满。实验室检查显示C反应蛋白为20mg/dL,腹部计算机断层扫描(CT)显示一家市级医院存在主动脉内漏,因此给予了4天的静脉注射阿莫西林/克拉维酸治疗,热退后出院。他因发热、寒战和水样腹泻1天入住我院。腹部CT显示左腰大肌脓肿与移植物感染有关。血培养生长出单核细胞增生李斯特菌。

诊断

由单核细胞增生李斯特菌菌血症引起的左腰大肌脓肿伴移植物感染。

干预措施

开具静脉注射氨苄西林联合协同庆大霉素治疗8天,反应良好。继续使用氨苄西林30天,然后改为静脉注射复方新诺明治疗12天。

结果

他保持无症状,C反应蛋白降至0.36mg/dL,红细胞沉降率降至39mm/h。他在住院第44天出院。开具口服复方新诺明治疗13.5个月。

经验教训

单核细胞增生李斯特菌引起主动脉移植物感染的病例报告很少。在某些特定病例中,特别是对于症状隐匿且手术风险高的患者,保留移植物并进行延长的抗菌治疗似乎是一种可行的初始治疗选择,必要时辅以经皮引流或手术清创。

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