Rivero Alexandra R, Fernández Israel, de Arellano Carmen Ramírez, Sierra Miguel A
J Org Chem. 2015 Jan 16;80(2):1207-13. doi: 10.1021/jo502292y.
The Sc(OTf)3-catalyzed [3 + 2]-annulation reaction between cyclopropenones and donor–acceptor cyclopropanes is described. The process leads directly to the formation of 4-oxaspiro[2.4]hept-1-ene derivatives in good to excellent reaction yields. Density functional theory calculations suggest that the [3 + 2]-annulation pathway is strongly preferred over the possible [3 + 3]-process.
描述了三氟甲磺酸钪催化的环丙烯酮与给体-受体环丙烷之间的[3+2]环化反应。该过程直接导致以良好至优异的反应产率形成4-氧杂螺[2.4]庚-1-烯衍生物。密度泛函理论计算表明，[3+2]环化途径比可能的[3+3]过程更具优势。
