Nair Aditya Gopinathan, Nair Akshay Gopinathan, Shah Bharat R, Gandhi Rashmin Anilkumar
Disha Psychiatric Clinic, Mumbai, India.
National Burns Institute, Mumbai, India.
Psychogeriatrics. 2015 Sep;15(3):204-8. doi: 10.1111/psyg.12091. Epub 2014 Dec 17.
Charles Bonnet syndrome (CBS) is a rare condition that encompasses three clinical features: complex visual hallucinations, ocular pathology causing visual deterioration, and preserved cognitive status. Common associated ocular pathologies include age-related macular degeneration, glaucoma, and cataracts. Several theories have been proposed to try to explain the visual hallucinations. However, the pathophysiology remains poorly understood, and treatment is largely based on anecdotal data. The lack of awareness of CBS among medical professionals often leads to inappropriate diagnosis and medication. In a country like India, where awareness of mental health is not widespread, cultural myths and stigma prevent patients from seeking professional help. Here we describe two cases of CBS and revisit different ocular morbidities that have been reported to occur in conjunction with CBS. Psychiatrists and ophthalmologists alike must be sensitive to this clinical condition to ensure prompt diagnosis and treatment.
查尔斯·邦尼特综合征（CBS）是一种罕见病症，包含三个临床特征：复杂视幻觉、导致视力减退的眼部病变以及认知状态保持正常。常见的相关眼部病变包括年龄相关性黄斑变性、青光眼和白内障。已经提出了几种理论来试图解释视幻觉。然而，其病理生理学仍知之甚少，治疗很大程度上基于轶事性数据。医学专业人员对CBS缺乏认识常常导致不恰当的诊断和用药。在像印度这样一个心理健康意识并不普及的国家，文化神话和污名阻碍患者寻求专业帮助。在此我们描述两例CBS病例，并回顾据报道与CBS同时发生的不同眼部疾病。精神科医生和眼科医生都必须对这种临床病症保持敏感，以确保及时诊断和治疗。
