Zhang Jinqing, Wang Shuo, Hong Jingfan, Liu Chunxiao, Jiang Yanbin
Department of Urology, Xiaolan Hospital of Southern Medical University, Zhongshan, 528415, China.
Urolithiasis. 2015 Apr;43(2):147-53. doi: 10.1007/s00240-014-0745-1. Epub 2014 Dec 17.
To find a more efficient solution for chemolysis of urinary calculi, several organic acids were chosen to form solutions by consulting the composition of a classic solution, Suby G. The solutions together with Renacidin, another classic solution, were designed to react with the 4 phosphate components of urinary stone. The processes were real-time measured and analysed by a focused beam reflectance measurement, and the efficiency factors were investigated and discussed in detail. The results show that several organic acids, e.g. hydroxyacetic acid, lactic acid and α-ketoglutaric acid, are more efficient than citric acid in dissolving urinary phosphate calculus. The new solutions containing the organic acids are promising for improving chemolysis treatment.
