Chandrasekar P H, Sluchak J A
Department of Medicine, Wayne State University, Detroit, Mich.
Chemotherapy. 1989;35(5):333-7. doi: 10.1159/000238691.
The in vitro activities of the newer agents Deptomycin, Difloxacin, A-56620 and Ciprofloxacin were compared with those of vancomycin, rifampin and gentamicin against methicillin-susceptible and -resistant Staphylococcus aureus and coagulase-negative staphylococci. All isolates were susceptible to vancomycin, rifampin, deptomycin and the quinolones tested. Newer agents had activity superior to that of vancomycin, whereas the activity of the newer agents and rifampin was comparable. Gentamicin resistance was frequent, however, the resistant staphylococci were susceptible to other antibiotics tested.
将新型药物去甲万古霉素、二氟沙星、A-56620和环丙沙星的体外活性与万古霉素、利福平及庆大霉素针对甲氧西林敏感和耐药金黄色葡萄球菌及凝固酶阴性葡萄球菌的活性进行了比较。所有分离株对万古霉素、利福平、去甲万古霉素及所测试的喹诺酮类药物均敏感。新型药物的活性优于万古霉素，而新型药物和利福平的活性相当。庆大霉素耐药情况较为常见，不过，耐药葡萄球菌对所测试的其他抗生素敏感。
