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某些抗菌剂对耐甲氧西林金黄色葡萄球菌的体外活性。

The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus.

作者信息

Moorhouse E C, Mulvihill T E, Jones L, Mooney D, Falkiner F R, Keane C T

出版信息

J Antimicrob Chemother. 1985 Mar;15(3):291-5. doi: 10.1093/jac/15.3.291.

Abstract

A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majority of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0.007 mg/l), while two newer compounds teichomycin and ciprofloxacin showed equal and appreciable activity (MIC90, 0.5 mg/l).

摘要

共对185株耐甲氧西林金黄色葡萄球菌进行了另外五种抗菌剂的敏感性研究。这些菌株中的绝大多数对庆大霉素和夫西地酸也耐药。利福平是所测试的最具活性的药物(MIC90,0.007毫克/升),而两种较新的化合物替考拉宁和环丙沙星显示出同等且显著的活性(MIC90,0.5毫克/升)。

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