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接受下壁ST段抬高型心肌梗死直接经皮冠状动脉介入治疗患者的罪犯血管与临床结局的关系。

The relationship between culprit artery and the clinical outcomes in patients undergoing primary percutaneous coronary ıntervention for ınferior wall ST segment elevation myocardial ınfarction.

作者信息

Ayhan Erkan, Isik Turgay, Ghannadian Bahman, Akgül Ozgur, Alagic Nermina

机构信息

Department of Cardiology, Medical Park Hospital, Bursa, Turkey -

出版信息

Minerva Cardioangiol. 2016 Aug;64(4):367-74. Epub 2014 Dec 17.

PMID:25516137
Abstract

BACKGROUND

We observed the effect of culprit artery in patients undergoing primary percutaneous coronary intervention (PCI) caused by inferior wall ST elevation myocardial infarction (STEMI) during hospital stay and 6-month follow-ups.

METHODS

After exclusion, 233 consecutive patients with inferior wall STEMI (mean age: 55.6±12.4 years) undergoing primary PCI were prospectively enrolled in this study. Patients were divided into two groups according to culprit artery: right coronary artery (RCA=group 1 [N.=187]) and left circumflex artery (LCX=group 2 [N.=46]). Patients were followed up for six months.

RESULTS

Patients of both groups had similar risk factors such as age, sex, hypertension and diabetes mellitus. While there were more cases of right ventricular infarction (P=0.001), complete atrioventricular block (P=0.002) and proximal located lesions (P=0.002) in RCA group, there was less collateral circulation incidence in LCX group (P=0.04). Ratios of no-reflow and myocardial blush grade after primary PCI were similiar in both groups. There was no significant difference between groups associated with major adverse cardiac events (MACE), target-vessel revascularization and mortality ratios during hospital stay and 6-month follow-up period.

CONCLUSIONS

The impact of RCA and LCX on MACE and cardiovascular mortality during hospital stay and the 6-month follow-up (mid-term) period are similar in patients on whom primary PCI was performed due to inferior wall STEMI.

摘要

背景

我们观察了下壁ST段抬高型心肌梗死(STEMI)患者在接受直接经皮冠状动脉介入治疗(PCI)时,罪犯血管对住院期间及6个月随访的影响。

方法

排除后,233例连续接受直接PCI的下壁STEMI患者(平均年龄:55.6±12.4岁)被前瞻性纳入本研究。根据罪犯血管将患者分为两组:右冠状动脉(RCA=第1组[N.=187])和左旋支动脉(LCX=第2组[N.=46])。对患者进行6个月的随访。

结果

两组患者在年龄、性别、高血压和糖尿病等危险因素方面相似。虽然RCA组右心室梗死(P=0.001)、完全性房室传导阻滞(P=0.002)和病变位于近端(P=0.002)的病例更多,但LCX组侧支循环发生率更低(P=0.04)。两组直接PCI后的无复流率和心肌灌注分级相似。在住院期间及6个月随访期,两组在主要不良心脏事件(MACE)、靶血管血运重建和死亡率方面无显著差异。

结论

对于因下壁STEMI接受直接PCI的患者,RCA和LCX在住院期间及6个月随访(中期)对MACE和心血管死亡率的影响相似。

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Medicine (Baltimore). 2020 Jun 26;99(26):e20152. doi: 10.1097/MD.0000000000020152.