Kemenesi Gábor, Zhang Dabing, Marton Szilvia, Dallos Bianka, Görföl Tamás, Estók Péter, Boldogh Sándor, Kurucz Kornélia, Oldal Miklós, Kutas Anna, Bányai Krisztián, Jakab Ferenc
Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, Hungary.
Virological Research Group, János Szentágothai Research Center, University of Pécs, Pécs, Hungary.
J Gen Virol. 2015 Apr;96(Pt 4):815-821. doi: 10.1099/jgv.0.000028. Epub 2014 Dec 16.
Bats are important reservoirs of many viruses with zoonotic potential worldwide, including Europe. Among bat viruses, members of the Picornaviridae family remain a neglected group. We performed viral metagenomic analyses on Miniopterus schreibersii bat faecal samples, collected in Hungary in 2013. In the present study we report the first molecular data and genomic characterization of a novel picornavirus from the bat species M. schreibersii in Europe. Based on phylogenetic analyses, the novel bat picornaviruses unambiguously belong to the Mischivirus genus and were highly divergent from other bat-derived picornaviruses of the Sapelovirus genus. Although the Hungarian viruses were most closely related to Mischivirus A, they formed a separate monophyletic branch within the genus.
蝙蝠是包括欧洲在内的全球许多具有人畜共患病潜力病毒的重要宿主。在蝙蝠病毒中，小RNA病毒科成员仍是一个被忽视的群体。我们对2013年在匈牙利采集的施氏长翼蝠粪便样本进行了病毒宏基因组分析。在本研究中，我们报告了欧洲施氏长翼蝠中一种新型小RNA病毒的首个分子数据和基因组特征。基于系统发育分析，新型蝙蝠小RNA病毒明确属于 Mischivirus 属，与 Sapelovirus 属其他蝙蝠来源的小RNA病毒高度不同。尽管匈牙利病毒与 Mischivirus A 关系最为密切，但它们在该属内形成了一个单独的单系分支。
