Manandhar D S, Sarkawi S, Hunt M C
Department of Paediatrics, Al Jahra Hospital, Kuwait.
Eur J Pediatr. 1989 Aug;148(8):761-3. doi: 10.1007/BF00443105.
A child is described with rickets and alopecia who did not respond to high doses of vitamin D3 but who responded to a small dose of 1-alpha-hydroxyvitamin D3. Treatment was continued for 2 years and then stopped. She has not shown any signs of relapse 1 year after stopping treatment. Her alopecia, however, has remained unchanged. One year after stopping treatment, her serum 25-hydroxycholecalciferol and parathormone levels were within normal limits but serum 1,25-dihydroxycholecalciferol was elevated.
一名患有佝偻病和脱发的儿童对大剂量维生素D3无反应，但对小剂量的1-α-羟基维生素D3有反应。治疗持续了2年，然后停止。停药1年后，她没有出现任何复发迹象。然而，她的脱发情况没有改变。停药1年后，她的血清25-羟胆钙化醇和甲状旁腺激素水平在正常范围内，但血清1,25-二羟胆钙化醇升高。
