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膀胱小细胞癌

Small cell carcinoma of the bladder.

作者信息

Calado Bruno Nagel, Maron Paulo Eduardo Goulart, Vedovato Bruno César, Barrese Tomas Zecchini, Fernandes Roni de Carvalho, Perez Marjo Deninson Cardenuto

机构信息

Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.

Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.

出版信息

Einstein (Sao Paulo). 2015 Jan-Mar;13(1):114-6. doi: 10.1590/S1679-45082014RC2975. Epub 2014 Dec 16.

DOI:10.1590/S1679-45082014RC2975
PMID:25517085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4946818/
Abstract

Small cell carcinoma of the urinary bladder is an extremely aggressive and rare tumor. Even though small cell carcinoma most commonly arises from the lungs there are several reports of small cell carcinoma in extrapulmonary sites. Due to its low frequency there is no well-established management for this disease. We report the case of a 61 year-old man with small cell carcinoma of the bladder who underwent radical cystectomy following neoadjuvant chemotherapy. We also reviewed the literature for the optimal treatment strategy.

摘要

膀胱小细胞癌是一种极具侵袭性的罕见肿瘤。尽管小细胞癌最常起源于肺部，但也有几例关于肺外部位小细胞癌的报道。由于其发病率低，目前尚无针对该疾病的成熟治疗方案。我们报告了一例61岁膀胱小细胞癌男性患者，其在新辅助化疗后接受了根治性膀胱切除术。我们还查阅了文献以寻找最佳治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/8d0dd021c8be/1679-4508-eins-13-1-114-gf03-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/3944ea4b7748/1679-4508-eins-13-1-114-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/957d75f7d099/1679-4508-eins-13-1-114-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/8d0dd021c8be/1679-4508-eins-13-1-114-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/3944ea4b7748/1679-4508-eins-13-1-114-gf01-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/957d75f7d099/1679-4508-eins-13-1-114-gf02-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/8d0dd021c8be/1679-4508-eins-13-1-114-gf03-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/3944ea4b7748/1679-4508-eins-13-1-114-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/957d75f7d099/1679-4508-eins-13-1-114-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/8d0dd021c8be/1679-4508-eins-13-1-114-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/3944ea4b7748/1679-4508-eins-13-1-114-gf01-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/957d75f7d099/1679-4508-eins-13-1-114-gf02-pt.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/4946818/8d0dd021c8be/1679-4508-eins-13-1-114-gf03-pt.jpg

相似文献

1
Small cell carcinoma of the bladder.膀胱小细胞癌
Einstein (Sao Paulo). 2015 Jan-Mar;13(1):114-6. doi: 10.1590/S1679-45082014RC2975. Epub 2014 Dec 16.
2
Urinary bladder carcinoma with divergent differentiation featuring small cell carcinoma, sarcomatoid carcinoma, and liposarcomatous component.具有小细胞癌、肉瘤样癌和脂肪肉瘤成分的分化异质性膀胱肿瘤。
Pathol Res Pract. 2016 Sep;212(9):833-7. doi: 10.1016/j.prp.2016.04.014. Epub 2016 May 18.
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Small cell carcinoma of the bladder: a case report and a literature review.膀胱小细胞癌：一例病例报告及文献综述
Arch Esp Urol. 2003 Mar;56(2):197-202.
4
[Small cell carcinoma of the urinary bladder: a case report].[膀胱小细胞癌：一例报告]
Hinyokika Kiyo. 2000 Jul;46(7):475-7.
5
[Primary small cell carcinoma of the bladder treated with partial cystectomy. Case report].
Actas Urol Esp. 2005 Oct;29(9):899-901. doi: 10.1016/s0210-4806(05)73362-3.
6
Early stage small cell carcinoma of the urinary bladder.
Int J Urol. 2001 Nov;8(11):643-4. doi: 10.1046/j.1442-2042.2001.00388.x.
7
[Small cell carcinoma of the urinary bladder: a case report].[膀胱小细胞癌：一例报告]
Hinyokika Kiyo. 2001 Oct;47(10):743-5.
8
[Small-cell carcinoma of the bladder: description of a case and review of the literature].[膀胱小细胞癌：一例病例报告及文献复习]
Arch Ital Urol Androl. 1994 Feb;66(1):57-60.
9
[Small cell carcinoma of the urinary bladder: a case report and review of the Japanese literature].[膀胱小细胞癌：一例报告并对日本文献的回顾]
Hinyokika Kiyo. 1997 Oct;43(10):739-42.
10
[Two cases of small cell carcinoma of the urinary bladder].[两例膀胱小细胞癌]
Hinyokika Kiyo. 1996 Aug;42(8):595-9.

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p53 Expression, Programmed Death Ligand 1, and Risk Factors in Urinary Tract Small Cell Carcinoma.p53表达、程序性死亡配体1与尿路小细胞癌的危险因素
Front Oncol. 2021 Apr 22;11:651754. doi: 10.3389/fonc.2021.651754. eCollection 2021.
2
Extrapulmonary small cell carcinoma of lymph node: Pooled analysis of all reported cases.淋巴结肺外小细胞癌：所有报告病例的汇总分析。
World J Clin Oncol. 2016 Jun 10;7(3):308-20. doi: 10.5306/wjco.v7.i3.308.

本文引用的文献

1
Small cell carcinoma of the urinary bladder: a rare, aggressive neuroendocrine malignancy.膀胱小细胞癌：一种罕见且侵袭性强的神经内分泌恶性肿瘤。
Arch Pathol Lab Med. 2012 Nov;136(11):1451-9. doi: 10.5858/arpa.2011-0267-RS.
2
Neuroendocrine tumours of the urinary system and male genital organs: clinical significance.泌尿系统和男性生殖器官的神经内分泌肿瘤：临床意义
BJU Int. 2009 Jun;103(11):1464-70. doi: 10.1111/j.1464-410X.2009.08451.x. Epub 2009 Feb 27.
3
Extrapulmonary small cell carcinoma of the bladder.膀胱肺外小细胞癌
Semin Oncol. 2007 Feb;34(1):15-21. doi: 10.1053/j.seminoncol.2006.10.025.
4
Clinical review - small cell carcinoma of the bladder.临床综述——膀胱小细胞癌
Cancer Treat Rev. 2006 Dec;32(8):588-93. doi: 10.1016/j.ctrv.2006.07.013. Epub 2006 Sep 27.
5
Small cell carcinoma of the urinary bladder. The Mayo Clinic experience.膀胱小细胞癌。梅奥诊所的经验。
Cancer. 2005 Mar 15;103(6):1172-8. doi: 10.1002/cncr.20903.
6
Small cell carcinoma of the urinary bladder: a clinicopathologic analysis of 64 patients.膀胱小细胞癌：64例患者的临床病理分析
Cancer. 2004 Sep 1;101(5):957-62. doi: 10.1002/cncr.20456.
7
Evidence supporting preoperative chemotherapy for small cell carcinoma of the bladder: a retrospective review of the M. D. Anderson cancer experience.支持膀胱小细胞癌术前化疗的证据：对MD安德森癌症中心经验的回顾性分析
J Urol. 2004 Aug;172(2):481-4. doi: 10.1097/01.ju.0000132413.85866.fc.
8
Small cell carcinoma of the bladder: long term outcome with integrated chemoradiation.膀胱小细胞癌：综合放化疗的长期疗效
Cancer. 1999 Dec 1;86(11):2346-52. doi: 10.1002/(sici)1097-0142(19991201)86:11<2346::aid-cncr24>3.0.co;2-5.
9
Small cell carcinoma of the urinary bladder treated with chemotherapy and radiotherapy: results in five cases.采用化疗和放疗治疗的膀胱小细胞癌：5例病例结果
Eur Urol. 1999 Apr;35(4):323-6. doi: 10.1159/000019870.
10
Genitourinary small cell carcinoma: determination of clinical and therapeutic factors associated with survival.泌尿生殖系统小细胞癌：与生存相关的临床和治疗因素的确定
J Urol. 1998 May;159(5):1624-9. doi: 10.1097/00005392-199805000-00058.