ESC 来源的视网膜色素上皮细胞移植治疗患者：目前为止，效果良好。
ESC-derived retinal pigmented epithelial cell transplants in patients: so far, so good.
机构信息
Stem Cells and Regenerative Medicine Section, UCL Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.
出版信息
Cell Stem Cell. 2014 Nov 6;15(5):537-8. doi: 10.1016/j.stem.2014.10.008.
PMID:25517461
Abstract
Many untreatable blinding diseases involve degeneration of retinal pigmented epithelial (RPE) cells, which has prompted exploration of the therapeutic potential of human-pluripotent-stem-cell-derived RPE. The first safety trials reported in The Lancet of embryonic-stem-cell-derived RPE cell transplants indicate no serious adverse outcomes and encourage further investigation.
摘要
许多无法治疗的致盲性疾病都涉及视网膜色素上皮 (RPE) 细胞的退化，这促使人们探索人多能干细胞衍生的 RPE 的治疗潜力。《柳叶刀》杂志报道的胚胎干细胞衍生的 RPE 细胞移植的首次安全性试验表明没有严重的不良后果，并鼓励进一步研究。
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