“我受够了”：耐多药结核病合并艾滋病患者既往抗结核治疗的经历
'I'm fed up': experiences of prior anti-tuberculosis treatment in patients with drug-resistant tuberculosis and HIV.
作者信息
Furin J, Isaakidis P, Reid A J, Kielmann K
机构信息
Tuberculosis Research Unit, Case Western Reserve University, Cleveland, Ohio, USA;
Médecins Sans Frontières (MSF), Mumbai, India.
出版信息
Int J Tuberc Lung Dis. 2014 Dec;18(12):1479-84. doi: 10.5588/ijtld.14.0277.
OBJECTIVES
To understand the impact of past experiences of anti-tuberculosis treatment among patients co-infected with the human immunodeficiency virus and multidrug-resistant tuberculosis (MDR-TB) on perceptions and attitudes towards treatment.
METHODS
Qualitative study using in-depth interviews with 12 HIV-MDR-TB co-infected patients in Mumbai, India.
RESULTS
Patients reported unnecessarily long pathways to care and fatigue with diagnostic and treatment procedures. In particular, they expressed concerns over the lack of efficacy of their current treatment regimen based on their experiences with anti-tuberculosis treatment regimens in the past.
CONCLUSION
Patients reported negative experiences with previous HIV and anti-tuberculosis treatment. Access to early diagnosis and rapid initiation of integrated care for HIV-MDR-TB co-infected patients, with a strong, patient-centered support system, could help to combat the low morale and lack of faith in treatment described in this group of patients.
目的
了解感染人类免疫缺陷病毒并患有耐多药结核病（MDR-TB）的患者过去的抗结核治疗经历对其治疗观念和态度的影响。
方法
采用定性研究方法，对印度孟买12例HIV-MDR-TB合并感染患者进行深入访谈。
结果
患者报告就医路径不必要地漫长，且对诊断和治疗程序感到疲惫。特别是，基于他们过去抗结核治疗方案的经历，他们对当前治疗方案的疗效缺乏表示担忧。
结论
患者报告了之前HIV和抗结核治疗的负面经历。为HIV-MDR-TB合并感染患者提供早期诊断并迅速启动综合治疗，以及建立一个强大的、以患者为中心的支持系统，可能有助于克服这组患者中出现的士气低落和对治疗缺乏信心的问题。
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