Liu Mai-lan, Chang Xiao-rong, Yuan Yi-qin
Zhen Ci Yan Jiu. 2014 Oct;39(5):422-6.
Following retrieving articles about foreign large sample clinical trials of acupuncture (more than 500 cases) from MEDLINE and EMBASE databases (1996-2012) by using keywords of "acupuncture" and "clinical trial", a quality analysis was carried out independently by two researchers. A total of 1373 papers were collected and 37 were considered to meet our preformulated standards in accordance with the principles and methods of evidence-based medicine. Majority of these 37 articles were from some advanced countries including Germany, USA, Japan, Demark, Australia, et al. Their paper quality and research quality are varied including the methodology, standards for diagnosis, inclusive and exclusive criteria, follow-up survey, economic effectiveness, adverse effects, acupoint application and syndrome differentiation of traditional Chinese medicine. Of the 37 papers, 17 are multiple center clinical trials, 18 are one center clinical trials, and 2 are not clear. Our Chinese researchers should pay more attention to foreign well-designed, large example, randomized controlled clinical trials and draw their matured experience and strong points to compensate our weak points and to improve our levels in clinical study on acupuncture treatment of clinical disorders.
通过使用“针灸”和“临床试验”作为关键词，从MEDLINE和EMBASE数据库（1996 - 2012年）中检索关于针灸的国外大样本临床试验（超过500例）的文章后，由两名研究人员独立进行质量分析。共收集到1373篇论文，按照循证医学的原则和方法，其中37篇被认为符合我们预先制定的标准。这37篇文章大多来自德国、美国、日本、丹麦、澳大利亚等一些发达国家。它们的论文质量和研究质量各不相同，包括方法学、诊断标准、纳入和排除标准、随访调查、经济效益、不良反应、穴位应用以及中医辨证等方面。在这37篇论文中，17篇为多中心临床试验，18篇为单中心临床试验，2篇情况不明。我国研究人员应更多关注国外设计良好、大样本、随机对照的临床试验，汲取其成熟经验和优点，弥补我们的不足，提高我国针灸治疗临床疾病的临床研究水平。
