Pinidbunjerdkool Akarachaid, Saengwanitch Sansanee, Sithinamsuwan Pasiri
J Med Assoc Thai. 2014 Feb;97 Suppl 2:S168-74.
To identify the frequency of behavioral and psychological symptoms of dementia (BPSD) and to explore the different characteristics between subgroup and severity of dementia.
Sixty-seven patients with Alzheimer's disease, vascular dementia, and mixed dementia were recruited to our cross-sectional study. Neuropsychiatric batteries including the Mini Mental Status Examination-Thai 2002, Thai Geriatric Depression Scale, 23 items from Alzheimer's Disease co-operative Study activities of daily living inventory, Behavioralpathology in Alzheimer's disease rating scale, and Pittsburg Sleep Quality Index were tested.
The most common behavioral and psychological symptoms of dementia (BPSD) were sleep problems (100%), paranoid/delusion (59.7%), diurnal disturbance (49.2%) and aggressiveness (46.3%). Hallucination and affective problems were more severe in AD than in VaD/mixed dementia. Sleep problems were identified more severe in mild dementia than moderate-to-severe dementia. With longer duration of having dementia, exceptfor affective problem, there was no diffemence in behavioral and psychological symptoms observed compared to the shorter dementia group.
Behavioral and psychological symptoms were very common in Alzheimer disease, vascular dementia, and mixed dementia. Since these symptoms cause cognitive and functional decline, institutionalization, caregiver distress and increase direct costs ofcare, the problem must be identified and addressed.
确定痴呆的行为和心理症状（BPSD）的发生率，并探讨痴呆亚组与严重程度之间的不同特征。
招募了67例阿尔茨海默病、血管性痴呆和混合性痴呆患者进行横断面研究。测试了包括2002年泰国简易精神状态检查表、泰国老年抑郁量表、阿尔茨海默病合作研究日常生活活动量表中的23项、阿尔茨海默病行为病理学评定量表和匹兹堡睡眠质量指数在内的神经精神量表。
痴呆最常见的行为和心理症状（BPSD）是睡眠问题（100%）、偏执/妄想（59.7%）、昼夜节律紊乱（49.2%）和攻击性（46.3%）。幻觉和情感问题在阿尔茨海默病中比在血管性痴呆/混合性痴呆中更严重。睡眠问题在轻度痴呆中比中度至重度痴呆中更严重。随着痴呆病程延长，除情感问题外，与痴呆病程较短的组相比，观察到的行为和心理症状没有差异。
行为和心理症状在阿尔茨海默病、血管性痴呆和混合性痴呆中非常常见。由于这些症状会导致认知和功能下降、住院、照顾者痛苦并增加护理直接成本，因此必须识别并解决该问题。
