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泰国癫痫患者的日间过度嗜睡和阻塞性睡眠呼吸暂停

Excessive daytime sleepiness and obstructive sleep apnea in Thai epileptic patients.

作者信息

Ruangkana Ponson, Chinvarun Yotin, Udommongkol Chesda, Chairungsaris Parnsiri, Nidhinandana Samart, Suwantamee Jithanorm, Sithinamsuwan Pasiri

出版信息

J Med Assoc Thai. 2014 Feb;97 Suppl 2:S175-80.

PMID:25518192
Abstract

BACKGROUND

Sleepiness is a common complaint in epilepsy. Also obstructive sleep apnea (OSA) is increasingly detected and would affect the epilepsy prognosis. We aimed to determine the frequency and predictors of sleepiness and OSA in epileptic patients.

MATERIAL AND METHOD

This was a cross-sectional descriptive study using Epworth Sleepiness Scale questionnaire (ESS) and Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) to identify excessive daytime sleepiness and OSA in our consecutive epileptic patients in Neurology out-patient clinic.

RESULTS

Overall 113 patients (male 55%) answered a personal survey and completed ESS and SA-SDQ. Mean age was 47 years (range 15-93). Average body mass index (BMI) was 24. Excessive daytime sleepiness (ESS 10) was demonstrated in 37%, and the prevalence of OSA diagnosed by using SA-SDQ was 20% (male 18%, female 22%). OSA were identified 68% among individuals whose BMI of more than 25, which was significant higherfi-equency than in the nomnnal BMI group (32%). The predictors of having OSA were older age and higher BMI. Epworth Sleepiness Scale score was also higher in the OSA group than in non-OSA group.

CONCLUSION

Excessive daytime sleepiness was identified around one third ofour epileptic individutals. Twenty percent had met the questionnaire criteria of having OSA. Overweight was the most important and modifiable risk factor ofOSA.

摘要

背景

嗜睡是癫痫患者常见的主诉。此外,阻塞性睡眠呼吸暂停(OSA)的检出率也日益增加,且会影响癫痫的预后。我们旨在确定癫痫患者嗜睡和OSA的发生率及预测因素。

材料与方法

这是一项横断面描述性研究,使用爱泼华嗜睡量表问卷(ESS)和睡眠障碍问卷中的睡眠呼吸暂停量表(SA-SDQ),对神经内科门诊连续就诊的癫痫患者进行日间过度嗜睡和OSA的识别。

结果

共有113例患者(男性占55%)接受了个人调查,并完成了ESS和SA-SDQ。平均年龄为47岁(范围15 - 93岁)。平均体重指数(BMI)为24。37%的患者存在日间过度嗜睡(ESS≥10),使用SA-SDQ诊断的OSA患病率为20%(男性18%,女性22%)。BMI大于25的个体中,OSA的检出率为68%,显著高于正常BMI组(32%)。OSA的预测因素为年龄较大和BMI较高。OSA组的爱泼华嗜睡量表评分也高于非OSA组。

结论

约三分之一的癫痫患者存在日间过度嗜睡。20%的患者符合OSA的问卷诊断标准。超重是OSA最重要且可改变的危险因素。

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