Severe vivax malaria: a case report and a literature review.

Most cases of severe malaria are caused by infection of Plasmodiumfalciparum. However severe manifestations in the infection of P. knowlesi and P. vivax have been reported in recentyears. The present study reported a 24-year-old Thai male presenting with acute fever and shock. Both blood smears and PCR were positive for P. vivax. He was treated with intravenous artesunate for 3 days in combination with oral mefloquine for 2 days and oral primaquine for 14 days. He was dischargedfrom hospital without any sequelae.