Zhang Shuang, Gao Hui-Le, Shen Shun, Wang Wei-Liang, Qian Jun
Yao Xue Xue Bao. 2014 Sep;49(9):1258-66.
As a new type of carbon nanomaterials, fluorescent carbon dots (fluorescent CDs) have many advantages when compared with the traditional fluorescent probes. They are photoluminescence stable and resistance to photo bleaching. Moreover, they are excellent in biocompatibility, low-toxic and easy to modify. All these above make them a promising optical image material as a probe in optical image. This article reviews structure, the common carbon sources, the preparation methods, and the light-emitting principles of the carbon dots. We also introduce the research progress of fluorescent carbon dots in biomedicine, and the problems need to be resolved in the study of fluorescent CDs.
作为一种新型碳纳米材料，荧光碳点与传统荧光探针相比具有诸多优势。它们光致发光稳定且抗光漂白。此外，它们具有优异的生物相容性、低毒性且易于修饰。上述所有特性使其成为一种很有前景的光学成像材料，可作为光学成像中的探针。本文综述了碳点的结构、常见碳源、制备方法及发光原理。我们还介绍了荧光碳点在生物医学领域的研究进展以及荧光碳点研究中需要解决的问题。
