Casseday J H, Kobler J B, Isbey S F, Covey E
Department of Surgery, Duke University, Durham, North Carolina 27710.
J Comp Neurol. 1989 Sep 8;287(2):247-59. doi: 10.1002/cne.902870208.
To determine the sources and targets of auditory pathways that bypass the inferior colliculus in the mustache bat, we injected WGA-HRP in the medial geniculate body and related auditory nuclei of the thalamus as well as in the lower brainstem. We used electrophysiological methods to verify that the injection electrode was in an area responsive to sound. The only thalamic injections that produced retrograde transport to cells in auditory nuclei caudal to the inferior colliculus were those that included the suprageniculate nucleus. These injections labeled a group of large multipolar cells lying between the ventral nucleus of the lateral lemniscus and the superior olivary complex. Neurons in this cell group have also been shown to project to the deep layers of the superior colliculus in the mustache bat. The pathway revealed by these studies is almost identical to the "central acoustic tract" in which fibers course medial to the lateral lemniscus and bypass the inferior colliculus to reach the deep superior colliculus and the suprageniculate nucleus.
为了确定在髯蝠中绕过下丘的听觉通路的来源和靶点，我们将WGA-HRP注射到内侧膝状体和丘脑相关听觉核以及低位脑干中。我们使用电生理方法来验证注射电极是否位于对声音有反应的区域。唯一能产生逆行运输至下丘尾侧听觉核细胞的丘脑注射部位是包含上膝状体核的部位。这些注射标记了一组位于外侧丘系腹侧核和上橄榄复合体之间的大型多极细胞。在髯蝠中，该细胞群中的神经元也已被证明投射至上丘深层。这些研究揭示的通路几乎与“中央听觉束”相同，其中纤维在外侧丘系内侧走行，绕过下丘以到达上丘深层和上膝状体核。
