Murphey R K, Possidente D R, Vandervorst P, Ghysen A
Department of Biology, State University of New York, Albany 12222.
J Neurosci. 1989 Sep;9(9):3209-17. doi: 10.1523/JNEUROSCI.09-09-03209.1989.
The legs of Drosophila are covered with mechanosensory bristles, innervated by sensory neurons that project to the CNS in a very orderly manner. We examined this afferent projection by staining the sensory neurons associated with identified bristles in wild-type, engrailed and scute flies. We observe that anterior neurons project to an anterior region of the ventral neuropil, while posterior neurons project to a more posterior region. We rule out that this difference depends on the compartment of origin of the receptors. Our results also argue against explanations based on other factors that might correlate to anterior/posterior position: peripheral organization of the leg nerve, competitive interactions, or differences in times of birth. We suggest that position itself is the primary determinant of this projection.
果蝇的腿部覆盖着机械感觉刚毛，由感觉神经元支配，这些感觉神经元以非常有序的方式投射到中枢神经系统。我们通过对野生型、engrailed和scute果蝇中与特定刚毛相关的感觉神经元进行染色，来研究这种传入投射。我们观察到，前部神经元投射到腹侧神经节的前部区域，而后部神经元投射到更靠后的区域。我们排除了这种差异取决于受体起源区域的可能性。我们的结果也反对基于其他可能与前后位置相关的因素的解释：腿部神经的外周组织、竞争相互作用或出生时间的差异。我们认为位置本身是这种投射的主要决定因素。
