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哥伦比亚自杀严重程度评定量表(C-SSRS):“金标准”是否已成为一种负担?

The Columbia-Suicide Severity Rating Scale (C-SSRS): Has the "Gold Standard" Become a Liability?

作者信息

Giddens Jennifer M, Sheehan Kathy Harnett, Sheehan David V

机构信息

J. Giddens is the Co-founder of the Tampa Center for Research on Suicidality, Tampa, Florida; Dr. K. Sheehan is Associate Professor Emeritus at the University of South Florida College of Medicine, Tampa, Florida; and Dr. D. Sheehan is Distinguished University Health Professor Emeritus at the University of South Florida College of Medicine, Tampa, Florida.

出版信息

Innov Clin Neurosci. 2014 Sep;11(9-10):66-80.

PMID:25520890
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4267801/
Abstract

OBJECTIVE

The Columbia- Suicide Severity Rating Scale has become the gold standard for the assessment of suicidal ideation and behavior in clinical trials. Criticism of the instrument has been mounting. We examine whether the instrument meets widely accepted psychometric standards and maps to the United States Food and Drug Administration's most recent 2012 algorithm for assessment of suicidal phenomena. Our goal is to determine if the Columbia-Suicide Severity Rating Scale should be retained as the preferred instrument for assessment of suicidal ideation and behavior.

METHOD

Standard psychometric criteria dictate that categorizations to avoid type I and type II errors should be comprehensive and address the full spectrum (i.e., all dimensions) of a phenomenon. The criteria should also be well defined and consistent, and the wording throughout should be unambiguous. We examine the Columbia-Suicide Severity Rating Scale in terms of these criteria.

RESULTS

The Columbia-Suicide Severity Rating Scale does not address the full spectrum of suicidal ideation or behavior. As a result, it has the potential to miss many combinations of suicidal ideation and behavior that present to clinicians in practice (type II error). Potential misclassifications (type I and II errors) are compounded by flawed navigation instructions; mismatches in category titles, definitions, and probes; and wording that is susceptible to multiple interpretations. Further, the Columbia-Suicide Severity Rating Scale in its current form does not map to the 2012 Food and Drug Administration's draft classification algorithm for suicidal ideation and behavior.

CONCLUSION

The evidence suggests that the Columbia-Suicide Severity Rating Scale is conceptually and psychometrically flawed and does not map to the Food and Drug Administration's new standards. A new gold standard for assessment of suicidality may be warranted.

摘要

目的

哥伦比亚自杀严重程度评定量表已成为临床试验中评估自杀意念和行为的金标准。对该工具的批评声越来越多。我们研究该工具是否符合广泛接受的心理测量标准,并与美国食品药品监督管理局2012年最新的自杀现象评估算法相对应。我们的目标是确定哥伦比亚自杀严重程度评定量表是否应继续作为评估自杀意念和行为的首选工具。

方法

标准的心理测量标准规定,为避免I型和II型错误进行的分类应全面,并涵盖现象的整个范围(即所有维度)。这些标准还应定义明确且一致,并且通篇措辞应清晰明了。我们根据这些标准来研究哥伦比亚自杀严重程度评定量表。

结果

哥伦比亚自杀严重程度评定量表未涵盖自杀意念或行为的整个范围。因此,它有可能遗漏临床实践中呈现给临床医生的许多自杀意念和行为组合(II型错误)。潜在的错误分类(I型和II型错误)因有缺陷的导航说明、类别标题、定义和探查问题不匹配以及易产生多种解释的措辞而更加复杂。此外,当前形式的哥伦比亚自杀严重程度评定量表与2012年美国食品药品监督管理局自杀意念和行为的分类算法草案不对应。

结论

证据表明,哥伦比亚自杀严重程度评定量表在概念和心理测量方面存在缺陷,并且与美国食品药品监督管理局的新标准不对应。可能需要一个评估自杀倾向的新金标准。

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本文引用的文献

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2
Do the Five Combinations of Suicidal Ideation in the FDA 2012 Draft Guidance Document and the C-SSRS Adequately Cover All Suicidal Ideation Combinations in Practice? A Case Study.美国食品药品监督管理局(FDA)2012年草案指南文件和哥伦比亚自杀严重程度评定量表(C-SSRS)中的自杀意念五种组合能否充分涵盖实践中的所有自杀意念组合?一项案例研究
Innov Clin Neurosci. 2014 Sep;11(9-10):172-8.
3
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4
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Innov Clin Neurosci. 2014 Sep;11(9-10):32-46.
5
Sheehan Suicidality Tracking Scale (S-STS): reliability, convergent and discriminative validity in young Italian adults.希恩自杀意念跟踪量表(S-STS):年轻意大利成年人中的信度、聚合和判别效度。
Compr Psychiatry. 2013 Oct;54(7):842-9. doi: 10.1016/j.comppsych.2013.03.012. Epub 2013 Apr 22.
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The Hamilton Rating Scale for Depression: The making of a "gold standard" and the unmaking of a chronic illness, 1960-1980.《汉密尔顿抑郁评定量表:一种“金标准”的形成与一种慢性病定义的消解,1960 - 1980年》
Chronic Illn. 2013 Sep;9(3):202-19. doi: 10.1177/1742395312467658. Epub 2012 Nov 21.
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Initial validity and reliability data on the Columbia-Suicide Severity Rating Scale.关于哥伦比亚自杀严重程度评定量表的初始效度和信度数据。
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The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults.哥伦比亚自杀严重程度评定量表:三项包含青少年和成年人的多中心研究的初步有效性和内部一致性结果。
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Feasibility and validation of a computer-automated Columbia-Suicide Severity Rating Scale using interactive voice response technology.利用交互式语音应答技术实现计算机自动化哥伦比亚-自杀严重程度评定量表的可行性和验证。
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The Treatment of Adolescent Suicide Attempters study (TASA): predictors of suicidal events in an open treatment trial.青少年自杀未遂者治疗研究(TASA):开放性治疗试验中自杀事件的预测因素。
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