Ridpath Alison, Driver Cynthia R, Nolan Michelle L, Karpati Adam, Kass Daniel, Paone Denise, Jakubowski Andrea, Hoffman Robert S, Nelson Lewis S, Kunins Hillary V
MMWR Morb Mortal Wkly Rep. 2014 Dec 19;63(50):1195-8.
Outdoor electronic dance-music festivals (EDMFs) are typically summer events where attendees can dance for hours in hot temperatures. EDMFs have received increased media attention because of their growing popularity and reports of illness among attendees associated with recreational drug use. MDMA (3,4-methylenedioxymethamphetamine) is one of the drugs often used at EDMFs. MDMA causes euphoria and mental stimulation but also can cause serious adverse effects, including hyperthermia, seizures, hyponatremia, rhabdomyolysis, and multiorgan failure. In this report, MDMA and other synthetic drugs commonly used at dance festivals are referred to as "synthetic club drugs." On September 1, 2013, the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) received reports of two deaths of attendees at an EDMF (festival A) held August 31-September 1 in NYC. DOHMH conducted an investigation to identify and characterize adverse events resulting in emergency department (ED) visits among festival A attendees and to determine what drugs were associated with these adverse events. The investigation identified 22 cases of adverse events; nine cases were severe, including two deaths. Twenty-one (95%) of the 22 patients had used drugs or alcohol. Of 17 patients with toxicology testing, MDMA and other compounds were identified, most frequently methylone, in 11 patients. Public health messages and strategies regarding adverse health events might reduce illnesses and deaths at EDMFs.
户外电子舞蹈音乐节(EDMFs)通常在夏季举办,参加者可以在炎热的天气中连续跳舞数小时。由于其日益普及以及有报道称参加者因使用消遣性药物而患病,EDMFs受到了媒体越来越多的关注。3,4-亚甲基二氧甲基苯丙胺(摇头丸)是EDMFs上经常使用的毒品之一。摇头丸会引起欣快感和精神兴奋,但也会导致严重的不良反应,包括体温过高、癫痫发作、低钠血症、横纹肌溶解和多器官功能衰竭。在本报告中,摇头丸和其他在舞蹈音乐节上常用的合成药物被称为“合成俱乐部毒品”。2013年9月1日,纽约市卫生和精神卫生部门(DOHMH)收到报告,称在8月31日至9月1日于纽约市举行的一场EDMF(音乐节A)上有两名参加者死亡。DOHMH展开调查,以确定和描述导致音乐节A参加者前往急诊科就诊的不良事件,并确定哪些药物与这些不良事件有关。调查发现了22起不良事件;其中9起较为严重,包括两起死亡。22名患者中有21名(95%)使用过药物或酒精。在17名接受毒理学检测的患者中,检测出了摇头丸和其他化合物,其中最常见的是甲烯二氧吡咯戊酮,有11名患者检测出该物质。关于不良健康事件的公共卫生信息和策略可能会减少EDMFs上的疾病和死亡情况。