儿童神经型布鲁氏菌病：来自土耳其的病例系列
Neurobrucellosis in children: Case series from Turkey.
作者信息
Teke Türkan Aydın, Koyuncu Hilal, Oz Fatma Nur, Metin Ozge, Bayhan Gülsüm Iclal, Aydın Zeynep Gökçe Gayretli, Kaman Ayşe, Tanır Gönül
机构信息
Department of Infectious Disease, Dr Sami Ulus Maternity and Children's Research and Education Hospital, Ankara, Turkey.
Department of Pediatrics, Dr Sami Ulus Maternity and Children's Research and Education Hospital, Ankara, Turkey.
出版信息
Pediatr Int. 2015 Aug;57(4):578-81. doi: 10.1111/ped.12510. Epub 2015 Feb 11.
BACKGROUND
Brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon and serious complication of pediatric brucellosis.
METHODS
We describe seven cases of neurobrucellosis.
RESULTS
Ataxia (one patient), diplopia (one patient) and hearing loss (one patient) were among the neurological signs and symptoms. The most common diagnoses were acute meningitis and meningoencephalitis. Five of the patients fully recovered, one was lost to follow up and the other had hearing loss as a sequela.
CONCLUSION
Neurobrucellosis should be kept in mind in patients with any neurological or neuropsychiatric diseases who live in endemic areas of brucellosis.
背景
布鲁氏菌病是一种多系统疾病，可能表现出广泛的临床表现和并发症。神经型布鲁氏菌病是小儿布鲁氏菌病罕见且严重的并发症。
方法
我们描述了7例神经型布鲁氏菌病病例。
结果
共济失调（1例患者）、复视（1例患者）和听力丧失（1例患者）属于神经体征和症状。最常见的诊断为急性脑膜炎和脑膜脑炎。5例患者完全康复，1例失访，另1例有听力丧失后遗症。
结论
对于生活在布鲁氏菌病流行地区且患有任何神经或神经精神疾病的患者，应考虑神经型布鲁氏菌病。
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