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中等质量证据表明,正畸治疗期间外科支抗比传统支抗更有效。

Moderate quality evidence that surgical anchorage more effective than conventional anchorage during orthodontic treatment.

作者信息

Reynders Reint Meursinge, de Lange Jan

机构信息

Department of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, The Netherlands.

出版信息

Evid Based Dent. 2014 Dec;15(4):108-9. doi: 10.1038/sj.ebd.6401060.

DOI:10.1038/sj.ebd.6401060
PMID:25522941
Abstract

DATA SOURCES

Cochrane Oral Health Groups Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, key international orthodontic and dental journals and the World Health Organization (WHO) International Clinical Trials Registry Platform.

STUDY SELECTION

Randomised controlled trials comparing surgical anchorage with conventional anchorage in orthodontic patients. Trials comparing two types of surgical anchorage were also included.

DATA EXTRACTION AND SYNTHESIS

Data extraction was performed independently and in duplicate by three review authors and the Cochrane risk of bias tool was used to assess bias. Random-effects meta-analysis was used for more than three studies when pooling of the data was clinically and statistically appropriate. Fixed-effect analysis was undertaken with two or three studies.

RESULTS

Fifteen studies, involving 543 analysed participants, were included. Five ongoing studies were identified. Eight studies were assessed to be at high overall risk of bias, six at unclear risk and one study at low risk of bias. Ten studies (407 randomised and 390 analysed patients) compared surgical anchorage with conventional anchorage for the primary outcome. A random-effects meta-analysis of seven studies for the primary outcome found strong evidence of an effect of surgical anchorage. Compared with conventional anchorage, surgical anchorage was more effective in the reinforcement of anchorage by 1.68 mm (95% CI -2.27 mm to -1.09 mm) (moderate quality evidence). This result should be interpreted with some caution, however, as there was a substantial degree of heterogeneity for this comparison. There was no evidence of a difference in overall duration of treatment between surgical and conventional anchorage (low quality of evidence).Information on patient-reported outcomes such as pain and acceptability was limited and inconclusive. When direct comparisons were made between two types of surgical anchorage, there was a lack of evidence to suggest that any one technique was better than another.

CONCLUSIONS

There is moderate quality evidence that reinforcement of anchorage is more effective with surgical anchorage than conventional anchorage, and that results from mini-screw implants are particularly promising. While surgical anchorage is not associated with the inherent risks and compliance issues related to extra-oral headgear, none of the included studies reported on harms of surgical or conventional anchorage.

摘要

数据来源

Cochrane口腔健康组试验注册库、Cochrane对照试验中央注册库(CENTRAL)、医学期刊数据库(Medline)、荷兰医学文摘数据库(Embase)、主要国际正畸与牙科杂志以及世界卫生组织(WHO)国际临床试验注册平台。

研究选择

比较正畸患者手术支抗与传统支抗的随机对照试验。比较两种手术支抗类型的试验也纳入其中。

数据提取与综合分析

由三位综述作者独立且重复地进行数据提取,并使用Cochrane偏倚风险工具评估偏倚。当数据合并在临床和统计学上适当时,对三项以上研究采用随机效应荟萃分析。对两项或三项研究进行固定效应分析。

结果

纳入15项研究,涉及543名分析对象。确定了5项正在进行的研究。8项研究被评估为总体偏倚风险高,6项风险不明,1项研究偏倚风险低。10项研究(407名随机分组患者和390名分析对象)比较了手术支抗与传统支抗的主要结局。对7项研究主要结局的随机效应荟萃分析发现,有强有力的证据表明手术支抗有效果。与传统支抗相比,手术支抗在增强支抗方面更有效,差值为1.68mm(95%可信区间-2.27mm至-1.09mm)(中等质量证据)。然而,由于该比较存在相当程度的异质性,对这一结果的解释应谨慎。没有证据表明手术支抗与传统支抗在总体治疗持续时间上存在差异(低质量证据)。关于患者报告结局如疼痛和可接受性的信息有限且无定论。当对两种手术支抗进行直接比较时,缺乏证据表明任何一种技术优于另一种。

结论

有中等质量证据表明,手术支抗在增强支抗方面比传统支抗更有效,微型螺钉种植体的效果尤其显著。虽然手术支抗不存在与口外支具相关的固有风险和依从性问题,但纳入的研究均未报告手术支抗或传统支抗的危害。

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本文引用的文献

1
Low quality evidence on the stability of orthodontic mini-implants.关于正畸微型种植体稳定性的低质量证据。
Evid Based Dent. 2013 Sep;14(3):78-80. doi: 10.1038/sj.ebd.6400950.
2
GRADE guidelines: 3. Rating the quality of evidence.GRADE 指南:3. 评估证据质量。
J Clin Epidemiol. 2011 Apr;64(4):401-6. doi: 10.1016/j.jclinepi.2010.07.015. Epub 2011 Jan 5.
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Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods.在正畸矫治器治疗期间,通过种植体或其他外科方法加强支抗。
用于诊断正畸微型种植体与牙根之间接触的植入扭矩记录:系统评价方案
Syst Rev. 2015 Apr 2;4:39. doi: 10.1186/s13643-015-0014-6.
Cochrane Database Syst Rev. 2007 Jul 18(3):CD005098. doi: 10.1002/14651858.CD005098.pub2.
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