扩散张量成像在放射性脊髓病中的应用

Diffusion Tensor Imaging in Radiation-Induced Myelopathy.

作者信息

Keřkovský Miloš, Zitterbartová Jana, Pour Luděk, Šprláková-Puková Andrea, Mechl Marek

机构信息

University Hospital Brno and Masaryk University, Department of Radiology, Central European Institute of Technology, Multimodal and Functional Imaging Laboratory.

Masaryk Memorial Cancer Institute, Department of Radiation Oncology.

出版信息

J Neuroimaging. 2015 Sep-Oct;25(5):836-40. doi: 10.1111/jon.12187. Epub 2014 Dec 18.

DOI:10.1111/jon.12187

PMID:25523302

Abstract

Radiation myelopathy (RM) is a rare complication of spinal cord irradiation. Diagnosis is based on the history of radiotherapy, laboratory tests, and magnetic resonance imaging of the spinal cord. The MRI findings may nevertheless be quite unspecific. In this paper, we describe the findings of diffusion tensor imaging in a case of the delayed form of RM. We observed areas of restricted diffusion within the spinal cord which probably corresponded to the ischemic changes. This would concur with the currently accepted pathogenetic theory concerning RM.

摘要

放射性脊髓病（RM）是脊髓照射的一种罕见并发症。诊断基于放疗史、实验室检查以及脊髓磁共振成像。然而，MRI表现可能相当不具特异性。在本文中，我们描述了一例迟发型RM患者的扩散张量成像结果。我们观察到脊髓内存在扩散受限区域，这可能与缺血性改变相对应。这与目前关于RM的公认发病机制理论相符。