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早期口腔内切口在颌周牙源性颌面脓肿患者中的价值。

The value of early intraoral incisions in patients with perimandibular odontogenic maxillofacial abscesses.

作者信息

Mücke Thomas, Dujka Nina, Ermer Michael A, Wolff Klaus-Dietrich, Kesting Marco, Mitchell David A, Ritschl Lucas, Deppe Herbert

机构信息

Department of Oral and Maxillofacial Surgery, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675 München, Germany.

Department of Oral and Maxillofacial Surgery, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675 München, Germany.

出版信息

J Craniomaxillofac Surg. 2015 Mar;43(2):220-3. doi: 10.1016/j.jcms.2014.11.009. Epub 2014 Nov 18.

Abstract

Perimandibular abscesses require drainage and removal of the underlying cause of infection. Traditionally drainage was established extraorally, but this can be associated with delay to treatment, because this is done under general anaesthesia. Between July 2008 and June 2013, 205 patients were initially either treated by immediate intraoral incision under local anaesthesia or extraoral incisions under general anaesthesia and prospectively evaluated. Predictors of treatment outcomes and complications were analysed. Fewer secondary procedures were needed for patients with primary treatment under general anaesthesia (p < 0.0001), but the overall stay in hospital was shorter after initial treatment under local anaesthesia (p < 0.0001, Odds Ratio (OR) 0.72, 95% CI 0.62-0.85). Postoperative complications occurred significantly more often under general anaesthesia (p < 0.0001, OR = 16.63, 95% CI 5.59-49.5). Significant prognostic variable was the administration of amoxicillin combined with clavulanic acid (p = 0.016, OR = 1.24, 95% CI 1.09-1.41) and adverse prognostic factors were infections with Human Immunodeficiency Virus (HIV) (p = 0.048, OR 17.45, 95% CI 1.02-298) or diabetes mellitus (p = 0.003, OR 10.39, 95% CI 2.23-48.41). Amoxicillin combined with clavulanic acid showed a significant impact on the treatment course of patients with perimandibular abscesses.

摘要

下颌周脓肿需要引流并去除潜在的感染病因。传统上引流是通过口外进行的,但这可能会导致治疗延迟,因为这是在全身麻醉下进行的。在2008年7月至2013年6月期间,对205例患者最初分别采用局部麻醉下即刻口内切开或全身麻醉下口外切开进行治疗,并进行前瞻性评估。分析了治疗结果和并发症的预测因素。全身麻醉下进行初始治疗的患者需要的二次手术较少(p<0.0001),但局部麻醉下初始治疗后的总体住院时间较短(p<0.0001,优势比(OR)0.72,95%可信区间0.62 - 0.85)。全身麻醉下术后并发症的发生明显更频繁(p<0.0001,OR = 16.63,95%可信区间5.59 - 49.5)。显著的预后变量是阿莫西林联合克拉维酸的使用(p = 0.016,OR = 1.24,95%可信区间1.09 - 1.41),不良预后因素是感染人类免疫缺陷病毒(HIV)(p = 0.048,OR 17.45,95%可信区间1.02 - 298)或糖尿病(p = 0.003,OR 10.39,95%可信区间2.23 - 48.41)。阿莫西林联合克拉维酸对下颌周脓肿患者的治疗过程有显著影响。

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