Luo Rui, Liu Jie, Hu Ping, Cheng Shu-Shu, Shi Bi-Zhen, Zhu Jian-Hua, Liu Ling
Department of Newborn Pediatrics, Guizhou Maternity and Child Care Hospital, Guiyang 550003, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2014 Dec;16(12):1197-201.
To determine the prevalence and risk factors of retinal diseases of preterm infants and full term for newborns small gestational age born (SGA) by using wide-angle digital retinal imaging system (RetCam3).
Clinical data of 779 preterm and SGA infants whose eyes were detected by RetCam3 between January and December 2013 before discharge were studied retrospectively.
Among the 779 infants, there were 69 cases of retinal hemorrhage (8.9%), 10 cases (1.3%) of retinopathy of prematurity (ROP), 9 cases of retinal exudative changes, 4 cases of retinal myelinated nerve fibers, 2 cases of congenita cataract, 3 cases of retinal chromatosis, 2 cases of retinal crystalline changes and 1 case of retinoblastoma. Logistic regression analysis indicated that low birth weight and gestational age and the history of oxygen inhalation were risk factors for the development of ROP and that vaginal delivery and mechanical ventilation increased the risk of retinal hemorrhage.
Neonatal fundus diseases may be so various and harmful that early fundus screening should be carried out on high-risk infants, such as preterm and SAG infants. Preventive measures should be taken against the risk factors for fundus diseases.
采用广角数字视网膜成像系统(RetCam3)确定早产儿及足月小样儿视网膜疾病的患病率及危险因素。
回顾性研究2013年1月至12月期间779例早产儿及小样儿出院前经RetCam3检查眼部的临床资料。
779例婴儿中,视网膜出血69例(8.9%),早产儿视网膜病变(ROP)10例(1.3%),视网膜渗出性改变9例,视网膜有髓神经纤维4例,先天性白内障2例,视网膜色素沉着3例,视网膜晶体样改变2例,视网膜母细胞瘤1例。Logistic回归分析表明,低出生体重、孕周及吸氧史是ROP发生的危险因素,阴道分娩及机械通气增加视网膜出血风险。
新生儿眼底疾病种类多样且危害大,应对早产儿及小样儿等高风险婴儿尽早进行眼底筛查,并针对眼底疾病危险因素采取预防措施。