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农民肺疾病主要病原体直丝糖多孢菌的基因组序列草图

Draft Genome Sequence of the Principal Etiological Agent of Farmer's Lung Disease, Saccharopolyspora rectivirgula.

作者信息

Barrera Coralie, Valot Benoît, Rognon Bénédicte, Zaugg Christophe, Monod Michel, Millon Laurence

机构信息

UMR 6249 Chrono-Environnement, University of Franche-Comté, Besançon, France

Dermatology Department, University Hospital, Lausanne, Switzerland.

出版信息

Genome Announc. 2014 Dec 18;2(6):e01340-14. doi: 10.1128/genomeA.01340-14.

DOI:10.1128/genomeA.01340-14
PMID:25523783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4271173/
Abstract

Saccharopolyspora rectivirgula is the main cause of farmer's lung disease. The development of recombinant antigens to standardize the serodiagnosis of the disease requires knowledge of the S. rectivirgula genome. We sequenced the genome of an environmental strain, S. rectivirgula DSM 43113. A total of 3,221 proteins were found to be encoded in a short 3.9-Mb genome.

摘要

直丝链霉菌是农民肺疾病的主要病因。开发重组抗原来规范该疾病的血清学诊断需要了解直丝链霉菌的基因组。我们对一株环境菌株直丝链霉菌DSM 43113的基因组进行了测序。在一个短的3.9兆碱基的基因组中总共发现编码了3221种蛋白质。

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Genome Announc. 2014 Dec 18;2(6):e01340-14. doi: 10.1128/genomeA.01340-14.
2
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本文引用的文献

1
Immunoreactive proteins of Saccharopolyspora rectivirgula for farmer's lung serodiagnosis.用于农民肺血清学诊断的直丝糖多孢菌免疫反应性蛋白
Proteomics Clin Appl. 2014 Dec;8(11-12):971-81. doi: 10.1002/prca.201400024. Epub 2014 Nov 4.
2
Draft Genome Sequence of Saccharopolyspora rectivirgula.直丝糖多孢菌基因组序列草图
Genome Announc. 2014 Jan 9;2(1):e01117-13. doi: 10.1128/genomeA.01117-13.
3
Myths and controversies in hypersensitivity pneumonitis.过敏性肺炎中的误区与争议
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Hypersensitivity pneumonitis.过敏性肺炎
Allergy. 2009 Mar;64(3):322-34. doi: 10.1111/j.1398-9995.2009.01949.x. Epub 2009 Feb 6.
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The spectrum of fungal allergy.真菌过敏的范围。
Int Arch Allergy Immunol. 2008;145(1):58-86. doi: 10.1159/000107578. Epub 2007 Aug 20.
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Needs and opportunities for research in hypersensitivity pneumonitis.过敏性肺炎的研究需求与机遇
Am J Respir Crit Care Med. 2005 Apr 1;171(7):792-8. doi: 10.1164/rccm.200409-1205WS. Epub 2005 Jan 18.
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Versatile and open software for comparing large genomes.用于比较大型基因组的通用且开放的软件。
Genome Biol. 2004;5(2):R12. doi: 10.1186/gb-2004-5-2-r12. Epub 2004 Jan 30.
8
FARMER'S LUNG. THERMOPHILIC ACTINOMYCETES AS A SOURCE OF "FARMER'S LUNG HAY" ANTIGEN.农民肺。嗜热放线菌作为“农民肺干草”抗原的来源。
Lancet. 1963 Sep 21;2(7308):607-11. doi: 10.1016/s0140-6736(63)90398-2.