Division of Neonatology, The Connecticut Human Milk Research Center, Connecticut Children's Medical Center, Hartford, CT; Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT.
Division of Neonatology, The Connecticut Human Milk Research Center, Connecticut Children's Medical Center, Hartford, CT; Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT.
J Pediatr. 2015 Mar;166(3):566-70.e1. doi: 10.1016/j.jpeds.2014.11.015. Epub 2014 Dec 16.
To quantify optimal minimum durations of exclusive breastfeeding associated with maintenance of any breastfeeding at 15 time points during the first year of life.
Mothers (n = 1189) from the prospective Infant Feeding Practices Study II cohort who initiated exclusive breastfeeding with healthy term infants were included. In a 80:20 split-sample validation study, receiver operating characteristic curves estimated optimal minimum durations of exclusive breastfeeding needed to predict maintenance of any breastfeeding at 15 time points during the first year (n = 951). Logistic regression estimated the predictive performance of the identified thresholds adjusted for maternal age, race, education, parity, support system, and return-to-work status. Results were validated in the remaining 20% (n = 238).
Optimal minimum durations ranged from 4.0-17.1 weeks of exclusive breastfeeding associated with maintenance of any breastfeeding at 15 time points. All estimated threshold durations were statistically significant after adjustment.
Using a methodological approach unique to breastfeeding duration research, the authors report optimal durations of exclusive breastfeeding associated with duration of any breastfeeding at time points throughout the first year. Perinatal clinicians, pediatricians, lactation professionals, policymakers, researchers, and families might apply these findings to achieve desirable collective breastfeeding duration outcomes.
量化与维持 1 岁内任何母乳喂养相关的纯母乳喂养的最佳最短持续时间，共涉及 15 个时间点。
纳入了前瞻性婴儿喂养实践研究 II 队列中最初用健康足月婴儿进行纯母乳喂养的母亲（n=1189）。在 80:20 拆分样本验证研究中，通过接收者操作特征曲线估计纯母乳喂养的最佳最短持续时间，以预测 1 年内 15 个时间点的任何母乳喂养维持情况（n=951）。通过逻辑回归，根据母亲的年龄、种族、教育、产次、支持系统和重返工作岗位的状况，对确定的阈值进行调整，以估计其预测性能。结果在剩余的 20%（n=238）中进行了验证。
最佳最短持续时间范围为 4.0-17.1 周的纯母乳喂养，与 15 个时间点的任何母乳喂养维持相关。所有估计的阈值持续时间在调整后均具有统计学意义。
作者使用一种独特的母乳喂养持续时间研究方法，报告了与 1 年内各时间点任何母乳喂养持续时间相关的纯母乳喂养的最佳最短持续时间。围产期临床医生、儿科医生、哺乳专家、政策制定者、研究人员和家庭可以应用这些发现来实现理想的集体母乳喂养持续时间结果。
