Athiyaman Hemalatha, Mayilvaganan Athiyaman, Singh Daleep
Department of Radiation Physics, Acharya Tulsi Regional Cancer Treatment and Research Institute, Sardar Patel Medical College and Associated Group of Hospitals, Bikaner, Rajasthan, India.
Department of Radiation Oncology, Acharya Tulsi Regional Cancer Treatment and Research Institute, Sardar Patel Medical College and Associated Group of Hospitals, Bikaner, Rajasthan, India.
J Med Phys. 2014 Oct;39(4):251-8. doi: 10.4103/0971-6203.144495.
A new planning method for Craniospinal Irradiation by Eclipse treatment planning system using Field alignment, Field-in-Field technique was developed. Advantage of this planning method was also studied retrospectively for previously treated five patients of medulloblastoma with variable spine length. Plan consists of half beam blocked parallel opposed cranium, and a single posterior cervicospine field was created by sharing the same isocenter, which obviates divergence matching. Further, a single symmetrical field was created to treat remaining Lumbosacral spine. Matching between a inferior diverging edge of cervicospine field and superior diverging edge of a Lumbosacral field was done using the field alignment option. 'Field alignment' is specific option in the Eclipse Treatment Planning System, which automatically matches the field edge divergence as per field alignment rule. Multiple segments were applied in both the spine field to manage with hot and cold spots created by varying depth of spinal cord. Plan becomes fully computerized using this field alignment option and multiple segments. Plan evaluation and calculated mean modified Homogeneity Index (1.04 and 0.1) ensured that dose to target volume is homogeneous and critical organ doses were within tolerance. Dose variation at the spinal field junction was verified using ionization chamber array (I'MatriXX) for matched, overlapped and gap junction spine fields; the delivered dose distribution confirmed the ideal clinical match, over exposure and under exposure at the junction, respectively. This method is simple to plan, executable in Record and Verify mode and can be adopted for various length of spinal cord with only two isocenter in shorter treatment time.
开发了一种利用Eclipse治疗计划系统,采用射野对齐、子野技术进行颅脊髓照射的新计划方法。还对之前治疗的5例脊柱长度各异的髓母细胞瘤患者进行了回顾性研究,以探讨该计划方法的优势。计划包括半束遮挡的平行相对颅野,通过共享相同的等中心创建单个后颈胸段脊柱野,从而避免了散度匹配。此外,创建单个对称野来治疗剩余的腰骶段脊柱。使用射野对齐选项来实现颈胸段脊柱野的下发散边缘与腰骶段野的上发散边缘之间的匹配。“射野对齐”是Eclipse治疗计划系统中的特定选项,它根据射野对齐规则自动匹配射野边缘散度。在两个脊柱野中均应用了多个子野,以处理因脊髓深度变化而产生的热点和冷点。使用该射野对齐选项和多个子野,计划实现了完全计算机化。计划评估和计算得出的平均修正均匀性指数(分别为1.04和0.1)确保了靶区剂量均匀,关键器官剂量在耐受范围内。使用电离室阵列(I'MatriXX)对匹配、重叠和间隙连接的脊柱野在脊髓野交界处的剂量变化进行了验证;所交付的剂量分布分别证实了交界处的理想临床匹配、过度照射和照射不足情况。该方法计划简单,可在记录与验证模式下执行,并且在较短的治疗时间内仅使用两个等中心即可适用于各种长度的脊髓。