Agah Jila, Baghani Roya, Safiabadi Tali Seid Hossein, Tabarraei Yaser
Department of Obstetrics & Gynecology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Department of Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran.
J Pregnancy. 2014;2014:245907. doi: 10.1155/2014/245907. Epub 2014 Nov 30.
Entonox (N2O2) which is an inhalational gas for relieving labor pain is commonly used intermittently; however some women are interested in continuous breathing in face mask. So we decided to compare the complications induced by two methods to find out whether it is safe to permit the mothers to use Entonox continuously or not.
This randomized clinical trial was performed in Mobini Hospital, Sabzevar, Iran. 50 parturients used Entonox intermittently and 50 cases used it continuously during labor. Then obstetrical outcomes were analyzed in two groups by spss 17 software, t-test, and Chi(2) while P < 0.05 was considered significant.
This study showed the mean duration of second stage of labor had no significant difference (P = 0.3). Perineal laceration was less in continuous group significantly (P = 0.04). Assisted vaginal birth was not different significantly (P = 0.4). Uterine atony had no significant difference in two groups (P = 0.2). Maternal collaboration in pushing and satisfaction were higher in continuous group significantly (P = 0.03), (P < 0.0001). Apgar score of neonates at first and fifth minute was acceptable and not different significantly in two groups (P = 0.3).
Our study demonstrated continuous method is also safe. So, it seems reasonable to set mothers free to choose the desired method of Entonox usage.
恩托诺克斯（N₂O₂）是一种用于缓解分娩疼痛的吸入性气体，通常间歇性使用；然而，一些女性对通过面罩持续呼吸感兴趣。因此，我们决定比较两种方法引起的并发症，以确定允许母亲持续使用恩托诺克斯是否安全。
这项随机临床试验在伊朗萨卜泽瓦尔的莫比尼医院进行。50名产妇在分娩期间间歇性使用恩托诺克斯，50名产妇持续使用。然后，使用SPSS 17软件、t检验和卡方检验对两组的产科结局进行分析，P < 0.05被认为具有统计学意义。
本研究表明，第二产程的平均持续时间无显著差异（P = 0.3）。持续使用组的会阴裂伤明显较少（P = 0.04）。辅助阴道分娩无显著差异（P = 0.4）。两组子宫收缩乏力无显著差异（P = 0.2）。持续使用组产妇在用力时的配合度和满意度明显更高（P = 0.03），（P < 0.0001）。新生儿出生后第1分钟和第5分钟的阿氏评分可接受，两组无显著差异（P = 0.3）。
我们的研究表明持续使用方法也是安全的。因此，可以合理地让母亲自由选择所需的恩托诺克斯使用方法。
