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复发性疼痛性肛周皮下血管样纤维组织细胞瘤:一例报告并文献复习

Recurrent painful perianal subcutaneous angiomatoid fibrous histiocytoma: a case report and review of the literature.

作者信息

Kong Xiangyi, Zhao Dachun, Lin Guole, Zhou Jiaolin, Cui Quancai

机构信息

From the Department of Neurosurgery (XK); Department of Pathology (DZ, QC); and Department of General Surgery (GL, JZ), Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Dongcheng District, Beijing, P.R. China.

出版信息

Medicine (Baltimore). 2014 Dec;93(28):e202. doi: 10.1097/MD.0000000000000202.

DOI:10.1097/MD.0000000000000202
PMID:25526437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4603136/
Abstract

Angiomatoid fibrous histiocytoma (AFH) is a rare, low-grade malignant soft-tissue tumor most commonly occurring in the extremities of children and young adults and has a low potential of local recurrence and metastasis. Here, we present a case of recurrent subcutaneous perianal AFH. After an initial diagnosis as a sebaceous cyst, we were able to use immunohistochemical findings to correctly identify the mass as an AFH. The patient was effectively treated after 3 surgical resections. This case emphasizes the need to correctly diagnose soft-tissue tumors using a variety of diagnostic modalities to ensure that the patient receives proper treatment.

摘要

血管样纤维组织细胞瘤(AFH)是一种罕见的低度恶性软组织肿瘤,最常见于儿童和青年成人的四肢,局部复发和转移的可能性较低。在此,我们报告一例复发性肛周皮下AFH病例。最初诊断为皮脂腺囊肿后,我们通过免疫组化结果正确地将该肿块鉴定为AFH。该患者经3次手术切除后得到有效治疗。本病例强调了需要使用多种诊断方法正确诊断软组织肿瘤,以确保患者得到恰当治疗。

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本文引用的文献

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Angiomatoid fibrous histiocytoma: an expansion of the clinical and histological spectrum.血管样纤维组织细胞瘤:临床与组织学谱的扩展
Pathology. 2014 Apr;46(3):199-204. doi: 10.1097/PAT.0000000000000073.
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WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition.世界卫生组织软组织肿瘤分类:基于 2013 年(第 4 版)的更新。
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Angiomatoid fibrous histiocytoma: a case report and review of the literature.血管样纤维组织细胞瘤:一例报告并文献复习
J Radiol Case Rep. 2012 Nov;6(11):8-15. doi: 10.3941/jrcr.v6i11.932. Epub 2012 Nov 1.
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Metastatic angiomatoid fibrous histiocytoma of the scalp, with EWSR1-CREB1 gene fusions in primary tumor and nodal metastasis.头皮转移性血管外皮细胞瘤样纤维组织细胞瘤,原发肿瘤和淋巴结转移中存在 EWSR1-CREB1 基因融合。
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Endobronchial pulmonary angiomatoid fibrous histiocytoma: two cases with EWSR1-CREB1 and EWSR1-ATF1 fusions.支气管肺血管外皮瘤样纤维组织细胞瘤:两例 EWSR1-CREB1 和 EWSR1-ATF1 融合。
Am J Surg Pathol. 2012 Jun;36(6):883-8. doi: 10.1097/PAS.0b013e31824b1ee0.
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Angiomatoid fibrous histiocytoma on the hard palate: case report.硬腭部血管样纤维组织细胞瘤:病例报告
Oral Maxillofac Surg. 2012 Jun;16(2):237-42. doi: 10.1007/s10006-011-0297-2. Epub 2011 Oct 1.
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