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胸腹主动脉瘤或夹层的血管内治疗后脊髓损伤

Spinal cord injury after endovascular treatment for thoracoabdominal aneurysm or dissection.

作者信息

Kato Masaaki, Motoki Manabu, Isaji Toshihiko, Suzuki Takahiro, Kawai Yusuke, Ohkubo Nobukazu

机构信息

Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan

Department of Cardiovascular Surgery, Morinomiya Hospital, Osaka, Japan.

出版信息

Eur J Cardiothorac Surg. 2015 Oct;48(4):571-7. doi: 10.1093/ejcts/ezu497. Epub 2014 Dec 18.

Abstract

OBJECTIVES

Postoperative spinal cord injury (SCI) is a devastating complication of surgical repair for thoracoabdominal aortic aneurysm or dissection (TAAD), despite the complex reconstruction of inter-costal or lumbar arteries involved in the surgery. As an alternative technique, endovascular thoracoabdominal aneurysm repair (EVTAR) with visceral artery reconstruction has been accepted as a treatment option for severe comorbid patients of TAAD, because there is a permissible frequency of SCI after EVTAR in spite of no reconstruction of inter-costal or lumbar arteries. We report the results of EVTAR at our hospital with a focus on spinal cord injury.

METHODS

We analyzed data from 54 consecutive patients with TAAD (mean age, 74 ± 9.6 years; 42 men) who underwent EVTAR at our hospital between February 2007 and February 2014. Three types of EVTAR technique were used: fenestrated and/or branched stent graft implantation in 39 patients, a hybrid technique (bypass grafts to visceral arteries and straight stent graft implantation) in 10 patients, and intentional coverage of the coeliac artery and straight stent graft implantation in 5 patients. In all patients, mean systemic blood pressure was maintained at ≥80 mmHg. Opioid use was avoided in the perioperative period.

RESULTS

According to the Crawford classification, the graft coverage extent was 9% (5/54) in type I, 11% (6/54) in type II, 39% (21/54) in type III, 22%(12/54) in type IV and 19% (10/54) in type V. In most patients (74%, 40/54), cerebrospinal fluid drainage was done intraoperatively and 1 day postoperatively. Hospital mortality was 5.6% (3/54). No patient developed SCI in the perioperative period. However, in the follow-up period 2 patients developed paraplegia as a consequence of shock caused by an aortic event.

CONCLUSIONS

With close attention to spinal cord protection, EVTAR may be associated with only a low incidence of SCI in the perioperative period. Therefore, EVTAR is expected to become a promising treatment option for appropriately selected patients with TAAD.

摘要

目的

尽管胸腹主动脉瘤或夹层(TAAD)手术修复涉及复杂的肋间或腰动脉重建,但术后脊髓损伤(SCI)仍是该手术极具破坏性的并发症。作为一种替代技术,带内脏动脉重建的血管腔内胸腹主动脉瘤修复术(EVTAR)已被视为TAAD严重合并症患者的一种治疗选择,因为尽管未重建肋间或腰动脉,但EVTAR术后SCI的发生率在可允许范围内。我们报告我院EVTAR的结果,重点关注脊髓损伤情况。

方法

我们分析了2007年2月至2014年2月期间在我院接受EVTAR的54例连续性TAAD患者(平均年龄74±9.6岁;42例男性)的数据。采用了三种类型的EVTAR技术:39例患者行开窗和/或分支支架植入术,10例患者行杂交技术(内脏动脉搭桥移植和直型支架植入),5例患者行腹腔干动脉有意覆盖和直型支架植入。所有患者的平均体循环血压维持在≥80 mmHg。围手术期避免使用阿片类药物。

结果

根据Crawford分类,I型移植物覆盖范围为9%(5/54),II型为11%(6/54),III型为39%(21/54),IV型为22%(12/54),V型为19%(10/54)。大多数患者(74%,40/54)在术中及术后1天进行了脑脊液引流。医院死亡率为5.6%(3/54)。围手术期无患者发生SCI。然而,在随访期间,2例患者因主动脉事件导致的休克而发生截瘫。

结论

密切关注脊髓保护,EVTAR在围手术期SCI的发生率可能较低。因此,对于适当选择的TAAD患者,EVTAR有望成为一种有前景的治疗选择。

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