用环孢素治疗一只患有糖尿病和充血性心力衰竭的猫的猫哮喘。
Treatment of feline asthma with ciclosporin in a cat with diabetes mellitus and congestive heart failure.
作者信息
Nafe Laura A, Leach Stacey B
机构信息
Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
出版信息
J Feline Med Surg. 2015 Dec;17(12):1073-6. doi: 10.1177/1098612X14563342. Epub 2014 Dec 19.
A 5-year-old domestic shorthair cat that had been previously diagnosed with diabetes mellitus was presented for episodes of coughing and respiratory distress. Diagnostic testing revealed congestive heart failure secondary to hypertrophic cardiomyopathy and concurrent asthma. All clinical signs and eosinophilic airway inflammation resolved with oral ciclosporin while the cat was concurrently receiving medications for treatment of heart failure (furosemide and enalapril). Ciclosporin should be considered for treatment of feline asthma in patients with concurrent diseases (eg, diabetes mellitus, severe heart disease) that may contraindicate use of oral glucocorticoid therapy.
一只5岁的家养短毛猫，此前被诊断患有糖尿病，因咳嗽和呼吸窘迫前来就诊。诊断测试显示，继发于肥厚性心肌病的充血性心力衰竭和并发哮喘。在这只猫同时接受治疗心力衰竭的药物（速尿和依那普利）时，口服环孢素后所有临床症状和嗜酸性气道炎症均得到缓解。对于患有可能禁忌使用口服糖皮质激素治疗的并发疾病（如糖尿病、严重心脏病）的猫哮喘患者，应考虑使用环孢素进行治疗。
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