（E）-2,6-双（1,1-二甲基乙基）-4-[2-（5-甲基-1H-吡唑-3-基）乙烯基]苯酚（PD 127443）的体内抗炎作用，5-脂氧合酶和环氧化酶的新型双重抑制剂。 - Suppr

Suppr

超能文献

The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.

作者信息

Schrier D J, Adamchak M A, Boctor A M, Kostlan C R, Flynn D L, Jordan J H, Lesch M E, Okonkwo G C

机构信息

Parke-Davis Pharmaceutical Research Division, Warner Lambert Co., Ann Arbor, MI 48105.

出版信息

Agents Actions. 1989 Jun;27(3-4):391-4. doi: 10.1007/BF01972831.

DOI:10.1007/BF01972831

PMID:2552768

Abstract

摘要

相似文献

The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.（E）-2,6-双（1,1-二甲基乙基）-4-[2-（5-甲基-1H-吡唑-3-基）乙烯基]苯酚（PD 127443）的体内抗炎作用，5-脂氧合酶和环氧化酶的新型双重抑制剂。

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引用本文的文献

Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability.BF-389的抗关节炎特性——一种具有低致溃疡风险的新型抗炎药。

Agents Actions. 1992 Sep;37(1-2):90-8. doi: 10.1007/BF01987895.

本文引用的文献

Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.角叉菜胶诱导大鼠后爪水肿作为抗炎药物的一种测定方法。

Proc Soc Exp Biol Med. 1962 Dec;111:544-7. doi: 10.3181/00379727-111-27849.

Adjuvant polyarthritis. IV. Induction by a synthetic adjuvant: immunologic, histopathologic, and other studies.佐剂性多关节炎。IV. 由一种合成佐剂诱导：免疫学、组织病理学及其他研究。

Arthritis Rheum. 1980 Jan;23(1):62-71. doi: 10.1002/art.1780230111.

Comparison in rats of the anti-inflammatory and gastric irritant effects of etodolac with several clinically effective anti-inflammatory drugs.依托度酸与几种临床有效的抗炎药物在大鼠体内抗炎及胃刺激性作用的比较。

Agents Actions. 1982 Jul;12(3):295-7. doi: 10.1007/BF01965392.

Leukotriene B4, polymorphonuclear leukocytes and inflammatory exudates in the rat.

Prostaglandins. 1984 Jul;28(1):13-27. doi: 10.1016/0090-6980(84)90110-2.

The anti=inflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide).异恶丙嗪（4-羟基-2-甲基-N-（5-甲基-3-异恶唑基-2H-1,2-苯并噻嗪-3-甲酰胺1,1-二氧化物）的抗炎特性。（注：原文中“anti=inflammatory”拼写有误，正确应为“anti-inflammatory”）

Agents Actions. 1975 Aug;5(3):256-63. doi: 10.1007/BF02026440.

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