（E）-2,6-双（1,1-二甲基乙基）-4-[2-（5-甲基-1H-吡唑-3-基）乙烯基]苯酚（PD 127443）的体内抗炎作用，5-脂氧合酶和环氧化酶的新型双重抑制剂。 - Suppr

Suppr

超能文献

The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.

作者信息

Schrier D J, Adamchak M A, Boctor A M, Kostlan C R, Flynn D L, Jordan J H, Lesch M E, Okonkwo G C

机构信息

Parke-Davis Pharmaceutical Research Division, Warner Lambert Co., Ann Arbor, MI 48105.

出版信息

Agents Actions. 1989 Jun;27(3-4):391-4. doi: 10.1007/BF01972831.

DOI:10.1007/BF01972831

PMID:2552768

Abstract

摘要

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The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.（E）-2,6-双（1,1-二甲基乙基）-4-[2-（5-甲基-1H-吡唑-3-基）乙烯基]苯酚（PD 127443）的体内抗炎作用，5-脂氧合酶和环氧化酶的新型双重抑制剂。

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