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印戒细胞窦组织细胞增多症。一种先前未被认识的组织学情况，在淋巴结中酷似转移性腺癌。

Signet ring cell sinus histiocytosis. A previously unrecognized histologic condition mimicking metastatic adenocarcinoma in lymph nodes.

作者信息

Gould E, Perez J, Albores-Saavedra J, Legaspi A

机构信息

Department of Pathology, University of Miami-Jackson Memorial Hospital, Florida.

出版信息

Am J Clin Pathol. 1989 Oct;92(4):509-12. doi: 10.1093/ajcp/92.4.509.

DOI:10.1093/ajcp/92.4.509
PMID:2552795
Abstract

The axillary lymph nodes in a radical mastectomy specimen from a 70-year-old insulin-dependent diabetic patient contained significantly vacuolated sinus histiocytes. The histologic picture closely resembled metastatic signet ring cell adenocarcinoma. The signet ring histiocytes did not stain with the mucicarmine or periodic acid-schiff stains or any of the immunohistochemical epithelial markers. The differential diagnosis and the possible origin of these vacuolated histiocytes are discussed.

摘要

一名70岁胰岛素依赖型糖尿病患者的根治性乳房切除标本中的腋窝淋巴结含有大量空泡化的窦组织细胞。组织学表现与转移性印戒细胞腺癌极为相似。印戒组织细胞对黏液卡红、过碘酸-希夫染色或任何免疫组化上皮标志物均无染色反应。本文讨论了这些空泡化组织细胞的鉴别诊断及可能来源。

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