神经振荡：运动网络中的β波段活动。

Neural oscillations: beta band activity across motor networks.

作者信息

Khanna Preeya, Carmena Jose M

机构信息

UC Berkeley - UCSF Joint Graduate Program in Bioengineering, USA.

UC Berkeley - UCSF Joint Graduate Program in Bioengineering, USA; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA.

出版信息

Curr Opin Neurobiol. 2015 Jun;32:60-7. doi: 10.1016/j.conb.2014.11.010. Epub 2014 Dec 17.

DOI:10.1016/j.conb.2014.11.010

PMID:25528615

Abstract

Local field potential (LFP) activity in motor cortical and basal ganglia regions exhibits prominent beta (15-40Hz) oscillations during reaching and grasping, muscular contraction, and attention tasks. While in vitro and computational work has revealed specific mechanisms that may give rise to the frequency and duration of this oscillation, there is still controversy about what behavioral processes ultimately drive it. Here, simultaneous behavioral and large-scale neural recording experiments from non-human primate and human subjects are reviewed in the context of specific hypotheses about how beta band activity is generated. Finally, a new experimental paradigm utilizing operant conditioning combined with motor tasks is proposed as a way to further investigate this oscillation.

摘要

在伸手、抓握、肌肉收缩和注意力任务期间，运动皮层和基底神经节区域的局部场电位（LFP）活动呈现出显著的β（15 - 40赫兹）振荡。虽然体外实验和计算研究揭示了可能导致这种振荡的频率和持续时间的特定机制，但对于最终驱动它的行为过程仍存在争议。在此，结合关于β波段活动如何产生的特定假设，对来自非人灵长类动物和人类受试者的同步行为和大规模神经记录实验进行综述。最后，提出一种利用操作性条件反射与运动任务相结合的新实验范式，作为进一步研究这种振荡的一种方法。