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[外阴癌的癌前病变及早期阶段]

[Precancerous conditions and early stages of vulvar cancer].

作者信息

Baltzer J

机构信息

I. Frauenklinik der Universität München.

出版信息

Arch Gynecol Obstet. 1989;245(1-4):498-503. doi: 10.1007/BF02417397.

DOI:10.1007/BF02417397
PMID:2552937
Abstract

Precancerous lesions and early stages of vulvar cancer are being increasingly observed in young women. Diagnosis is possible by means of clinical examination, colposcopy, cytology, and specific biopsy. From a prognostic and therapeutic point of view it is important to differentiate between preneoplastic and early invasive squamous cell carcinoma and to remove the lesion completely. In the case of patients with vulvar stage A carcinoma, an organ-conserving surgical procedure is justified, since a metastatic invasion of the regional lymph nodes would seem unlikely. In the case of patients with carcinoma beyond this definition an individualized tumor treatment is undertaken taking account of defined morphological prognostic criteria.

摘要

在外阴癌的癌前病变和早期阶段越来越多地在年轻女性中被观察到。通过临床检查、阴道镜检查、细胞学检查和特异性活检可以进行诊断。从预后和治疗的角度来看,区分肿瘤前和早期浸润性鳞状细胞癌并完全切除病变很重要。对于外阴A期癌患者,保留器官的手术是合理的,因为区域淋巴结发生转移浸润的可能性似乎不大。对于超出此定义的癌患者,则根据明确的形态学预后标准进行个体化肿瘤治疗。

相似文献

1
[Precancerous conditions and early stages of vulvar cancer].[外阴癌的癌前病变及早期阶段]
Arch Gynecol Obstet. 1989;245(1-4):498-503. doi: 10.1007/BF02417397.
2
[Precancerous and early stages of vulvar cancer].[外阴癌的癌前病变及早期阶段]
Gynakol Geburtshilfliche Rundsch. 1992;32 Suppl 1:14. doi: 10.1159/000271922.
3
[Therapeutic recommendations for intra-epithelial neoplasms of the vulva].[外阴上皮内瘤变的治疗建议]
Arch Gynecol Obstet. 1991;249 Suppl:S64-7.
4
[Surgical therapy of premalignant and malignant diseases of the vulva].[外阴癌前病变及恶性疾病的外科治疗]
Gynakol Geburtshilfliche Rundsch. 1992;32 Suppl 1:15-8. doi: 10.1159/000271923.
5
Epithelial alterations adjacent to invasive squamous carcinoma of the vulva.外阴浸润性鳞状细胞癌旁的上皮改变
J Reprod Med. 1994 Jul;39(7):526-30.
6
[Premalignant vulvar lesions].[外阴癌前病变]
Gynakologe. 1993 Sep;26(4):267-74.
7
[Detection of human papilloma virus (HPV) DNA in vulvar cancers].
Geburtshilfe Frauenheilkd. 1988 Nov;48(11):776-80. doi: 10.1055/s-2008-1026625.
8
Absence of p53 protein overexpression in precancerous lesions of the vulva.外阴癌前病变中p53蛋白无过表达。
Cancer. 1998 Jan 15;82(2):323-7. doi: 10.1002/(sici)1097-0142(19980115)82:2<328::aid-cncr12>3.0.co;2-0.
9
[Early cancer detection--advanced vulvar cancer: a contradiction?].[早期癌症检测——晚期外阴癌:自相矛盾?]
Zentralbl Gynakol. 1993;115(10):466-7.
10
[Vulvar squamous precancerous lesions History and current state of the topic].[外阴鳞状上皮癌前病变 该主题的历史与现状]
Ceska Gynekol. 2016 Summer;81(3):172-176.

本文引用的文献

1
Microinvasive carcinoma of the vulva.外阴微小浸润癌
Int J Gynecol Pathol. 1982;1(1):29-39. doi: 10.1097/00004347-198201000-00005.
2
Vulvar carcinoma in situ.外阴原位癌。
Obstet Gynecol. 1983 Mar;61(3):304-7.
3
Microinvasive squamous carcinoma of the vulva: present status and reassessment.外阴微小浸润性鳞状细胞癌:现状与重新评估
Gynecol Oncol. 1984 May;18(1):71-6. doi: 10.1016/0090-8258(84)90008-8.
4
Human papillomavirus and herpes simplex virus in vulvar squamous cell carcinoma in situ.
Am J Obstet Gynecol. 1988 Apr;158(4):862-71. doi: 10.1016/0002-9378(88)90086-5.