Baltzer J
I. Frauenklinik der Universität München.
Arch Gynecol Obstet. 1989;245(1-4):498-503. doi: 10.1007/BF02417397.
Precancerous lesions and early stages of vulvar cancer are being increasingly observed in young women. Diagnosis is possible by means of clinical examination, colposcopy, cytology, and specific biopsy. From a prognostic and therapeutic point of view it is important to differentiate between preneoplastic and early invasive squamous cell carcinoma and to remove the lesion completely. In the case of patients with vulvar stage A carcinoma, an organ-conserving surgical procedure is justified, since a metastatic invasion of the regional lymph nodes would seem unlikely. In the case of patients with carcinoma beyond this definition an individualized tumor treatment is undertaken taking account of defined morphological prognostic criteria.
在外阴癌的癌前病变和早期阶段越来越多地在年轻女性中被观察到。通过临床检查、阴道镜检查、细胞学检查和特异性活检可以进行诊断。从预后和治疗的角度来看,区分肿瘤前和早期浸润性鳞状细胞癌并完全切除病变很重要。对于外阴A期癌患者,保留器官的手术是合理的,因为区域淋巴结发生转移浸润的可能性似乎不大。对于超出此定义的癌患者,则根据明确的形态学预后标准进行个体化肿瘤治疗。