Salari Pooneh, Abdollahi Mohammad
Medical Ethics and History of Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ; Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran ; Endocrinology & Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran.
J Family Reprod Health. 2014 Dec;8(4):135-48.
Osteoporosis is considered as an important public health problem especially in postmenopausal women. There are some hypotheses support the contributory effect of pregnancy and lactation on osteoporosis later in life. High calcium demand during pregnancy and lactation and low estrogenic state support those hypotheses. Numerous studies have investigated on the issue but there is no consensus about the contributory effect of pregnancy and lactation on osteoporosis. To explore the current state of fact, in the present study, all bibliographic databases were searched and all relevant studies on the topic of osteoporosis, lactation, and pregnancy were reviewed. The review shows that despite of controversial results, pregnancy may have protective effect on bone especially if followed by lactation.
骨质疏松症被视为一个重要的公共卫生问题,尤其是在绝经后女性中。有一些假说支持怀孕和哺乳对晚年骨质疏松症的促成作用。怀孕和哺乳期间对钙的高需求以及低雌激素状态支持了这些假说。许多研究都对这个问题进行了调查,但关于怀孕和哺乳对骨质疏松症的促成作用尚无共识。为了探究当前的实际情况,在本研究中,检索了所有书目数据库,并对所有关于骨质疏松症、哺乳和怀孕主题的相关研究进行了综述。综述表明,尽管结果存在争议,但怀孕可能对骨骼有保护作用,尤其是在随后进行哺乳的情况下。