英夫利昔单抗治疗粟粒性肺结核停药后发生肺栓塞
Pulmonary Embolism following Cessation of Infliximab for Treatment of Miliary Tuberculosis.
作者信息
Lee Brian, Moosavy Farid
机构信息
Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA.
Attending, Pulmonary and Critical Care Section, Christiana Care Health System, 4745 Ogletown-Stanton Road, Map 1, Suite 220, Newark, DE 19713, USA.
出版信息
Case Rep Pulmonol. 2014;2014:479025. doi: 10.1155/2014/479025. Epub 2014 Oct 29.
Abstract
We report a case of a 41-year-old male who presented with tachycardia and swelling of his left arm six weeks after he started antituberculosis treatment and stopped his rheumatoid arthritis infliximab treatment. He was diagnosed with pulmonary embolism by chest CT and initially treated with warfarin, which interacted with his antituberculosis treatment. This presentation of deep vein thrombosis and pulmonary embolism as part of immune reconstitution inflammatory syndrome has not been previously reported for infliximab treated patients.
摘要
我们报告一例41岁男性病例，该患者在开始抗结核治疗并停止使用类风湿关节炎英夫利昔单抗治疗六周后，出现心动过速和左臂肿胀。通过胸部CT诊断为肺栓塞，最初使用华法林治疗，而华法林与他的抗结核治疗存在相互作用。作为免疫重建炎症综合征一部分的深静脉血栓形成和肺栓塞的这种表现，此前尚未在接受英夫利昔单抗治疗的患者中报道过。
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