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英夫利昔单抗治疗粟粒性肺结核停药后发生肺栓塞

Pulmonary Embolism following Cessation of Infliximab for Treatment of Miliary Tuberculosis.

作者信息

Lee Brian, Moosavy Farid

机构信息

Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA.

Attending, Pulmonary and Critical Care Section, Christiana Care Health System, 4745 Ogletown-Stanton Road, Map 1, Suite 220, Newark, DE 19713, USA.

出版信息

Case Rep Pulmonol. 2014;2014:479025. doi: 10.1155/2014/479025. Epub 2014 Oct 29.

DOI:10.1155/2014/479025
PMID:25530902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4228825/
Abstract

We report a case of a 41-year-old male who presented with tachycardia and swelling of his left arm six weeks after he started antituberculosis treatment and stopped his rheumatoid arthritis infliximab treatment. He was diagnosed with pulmonary embolism by chest CT and initially treated with warfarin, which interacted with his antituberculosis treatment. This presentation of deep vein thrombosis and pulmonary embolism as part of immune reconstitution inflammatory syndrome has not been previously reported for infliximab treated patients.

摘要

我们报告一例41岁男性病例,该患者在开始抗结核治疗并停止使用类风湿关节炎英夫利昔单抗治疗六周后,出现心动过速和左臂肿胀。通过胸部CT诊断为肺栓塞,最初使用华法林治疗,而华法林与他的抗结核治疗存在相互作用。作为免疫重建炎症综合征一部分的深静脉血栓形成和肺栓塞的这种表现,此前尚未在接受英夫利昔单抗治疗的患者中报道过。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c2/4228825/779635c814ab/CRIPU2014-479025.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c2/4228825/a924b6161c9a/CRIPU2014-479025.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c2/4228825/779635c814ab/CRIPU2014-479025.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c2/4228825/a924b6161c9a/CRIPU2014-479025.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c2/4228825/779635c814ab/CRIPU2014-479025.002.jpg

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Steroids Decrease Prevalence of Positive Tuberculin Skin Test in Rheumatoid Arthritis: Implications on Anti-TNF Therapies.类固醇降低类风湿关节炎患者结核菌素皮肤试验阳性率:对肿瘤坏死因子拮抗剂治疗的影响
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抗 TNF 治疗的类风湿关节炎患者的结核药物特异性风险:来自英国风湿病学会生物制剂注册处(BSRBR)的结果。
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Mycobacterium other than tuberculosis (MOTT) infection: an emerging disease in infliximab-treated patients.非结核分枝杆菌(MOTT)感染:英夫利昔单抗治疗患者中的一种新出现的疾病。
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Paradoxical response to antituberculous therapy in infliximab-treated patients with disseminated tuberculosis.英夫利昔单抗治疗的播散性肺结核患者对抗结核治疗的矛盾反应。
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