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Slip and leak in mitochondrial oxidative phosphorylation.

作者信息

Murphy M P

机构信息

Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY.

出版信息

Biochim Biophys Acta. 1989 Nov 23;977(2):123-41. doi: 10.1016/s0005-2728(89)80063-5.

Abstract

During oxidative phosphorylation by mammalian mitochondria part of the free energy stored in reduced substrates is dissipated and energy is released as heat. Here I review the mechanisms and the physiological significance of this phenomenon.

摘要

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