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[孕期经历异相睡眠剥夺的大鼠后代大脑皮质突触膜上[³H]蝇蕈醇结合的特征]

[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].

作者信息

Zhulin V V, Zabludovskiĭ A L

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1989(6):54-6.

PMID:2553136
Abstract

White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy. [3H]muscimol binding level of neocortex synaptosomal membranes was significantly higher in their offsprings as compared with the control ones. Possible ways of GABA-ergic system malformations are discussed.

摘要

在妊娠14至20天期间，对白鼠进行快速眼动睡眠剥夺。与对照组相比，其后代新皮质突触体膜的[3H]蝇蕈醇结合水平显著更高。文中讨论了γ-氨基丁酸能系统畸形的可能途径。

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