Surapuram Venkatasaichaitanya, Setzer William N, McFeeters Robert L, McFeeters Hana
Nat Prod Commun. 2014 Nov;9(11):1603-5.
Despite recent advances in antifungal development, fungi remain a devastating threat to human health and compromise viability of the food supply. Plant based antimicrobials represent a vast untapped source with tremendous potential. Herein we present the antifungal properties of more than 50 plant extracts against two important human and agricultural pathogens, Aspergillus niger and Rhizopus stolonifer. Multiple extracts exhibit promising MIC values of less than 100 μg/mL and are reported for both fungal species.
尽管近期在抗真菌药物研发方面取得了进展,但真菌仍然对人类健康构成毁灭性威胁,并危及食物供应的生存能力。植物源抗菌剂是一个巨大的未开发资源,具有巨大潜力。在此,我们展示了50多种植物提取物对两种重要的人类和农业病原体——黑曲霉和匍枝根霉的抗真菌特性。多种提取物对这两种真菌均表现出小于100μg/mL的有前景的最低抑菌浓度(MIC)值。