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肾和心脏同种异体移植前后及感染时的血清β2-微球蛋白

Serum beta 2-microglobulin before and after renal and heart allotransplantation and in infection.

作者信息

Korcáková L, Svobodová J, Sedlácková E, Kaslík J, Kaslíková J, Horák J, Fabián J, Kocandrle V

机构信息

Institute for Clinical and Experimental Medicine, Prague.

出版信息

Czech Med. 1989;12(3):158-61.

PMID:2553359
Abstract

UNLABELLED

beta 2-microglobulin (beta 2-m) serum levels were significantly elevated in patients waiting for kidney transplantation. The levels decreased after successful transplantation, even when they were never as low as in a control group of healthy blood donors. A higher amount of serum (s-) beta 2-m was observed also in heart transplant recipients. A significant reincrease in s-beta 2-m occurred during rejection of renal allograft and during CMV and EBV infection. The levels of s-beta 2-m were higher in patients infected with CMV than in those infected with EBV.

ABBREVIATIONS

beta 2-m = beta 2-microglobulin, s-beta 2-m = serum beta 2-microglobulin, CMV = cytomegalovirus, EBV = Epstein-Barr virus.

摘要

未标记

等待肾移植的患者血清β2-微球蛋白(β2-m)水平显著升高。成功移植后该水平下降,即便其从未低至健康献血者对照组的水平。心脏移植受者中也观察到较高水平的血清(s-)β2-m。肾移植排斥反应期间以及巨细胞病毒(CMV)和EB病毒(EBV)感染期间,s-β2-m显著再次升高。感染CMV的患者s-β2-m水平高于感染EBV的患者。

缩写

β2-m = β2-微球蛋白,s-β2-m = 血清β2-微球蛋白,CMV = 巨细胞病毒,EBV = EB病毒

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