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[昏迷后播散性多发性神经病]

[Disseminated polyneuropathy after coma].

作者信息

Grahmann F, Neundörfer B, Erbguth F

机构信息

Neurologische Klinik, Universität Erlangen-Näunberg.

出版信息

Dtsch Med Wochenschr. 1989 Oct 27;114(43):1658-61. doi: 10.1055/s-2008-1066811.

Abstract

An acute polyneuropathy developed during intensive-care treatment of three young men who had sustained severe multiple traumas and of one woman with bacterial meningoencephalitis. In the first case there was a predominantly distal paraparesis of the legs; in the second, flaccid neurological deficits occurred particularly in the areas of the left ulnar, peroneal and tibial nerves combined with paralysis of cranial nerves IX, X and XII. A symmetrical sensorimotor polyneuropathy with tetraplegia and cranial nerve deficits occurred in the third case, and an asymmetrical sensorimotor polyneuropathy in the female patient. In all four patients electrophysiological tests demonstrated the pattern of neurogenic damage. All patients had respiratory failure, malnutrition, septic fevers and acute renal failure requiring haemodialysis for two to five weeks. It is assumed that the polyneuropathy was of multifactorial genesis.

摘要

三名遭受严重多发伤的年轻男性以及一名患有细菌性脑膜脑炎的女性在重症监护治疗期间发生了急性多发性神经病。第一例主要表现为双下肢远端轻瘫;第二例出现弛缓性神经功能缺损,尤其在左侧尺神经、腓总神经和胫神经分布区域,并伴有第九、十和十二对脑神经麻痹。第三例出现对称性感觉运动性多发性神经病伴四肢瘫和脑神经缺损,而女性患者则为不对称性感觉运动性多发性神经病。所有四名患者的电生理检查均显示神经源性损伤模式。所有患者均出现呼吸衰竭、营养不良、败血症发热以及急性肾衰竭,需要进行两到五周的血液透析。推测该多发性神经病是多因素成因。

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