Wernersson Rebecca, Carlsson Jessica
Det Sundhedsvidenskablige Fakultet, Københavns Universitet.
Ugeskr Laeger. 2014 Dec 15;176(51).
Stress influences the whole body, including the gut. Irritable bowel syndrome (IBS) is a syndrome characterized by gastrointestinal symptoms, with the absence of clinical signs. IBS is seen in several psychiatric co-morbidities. Only few studies have examined the association between IBS and posttraumatic stress disorder (PTSD). There are several hypotheses of how this association can be explained, e.g. oxytocin dysregulation, hypothalamic-pituitary-adrenal axis dysfunction, the vulnerability of the patient group, post-infectious irritable bowel and side effects of the medical treatment of PTSD.
压力会影响全身,包括肠道。肠易激综合征(IBS)是一种以胃肠道症状为特征但无临床体征的综合征。肠易激综合征在几种精神共病中较为常见。仅有少数研究探讨了肠易激综合征与创伤后应激障碍(PTSD)之间的关联。关于如何解释这种关联有几种假说,例如催产素失调、下丘脑 - 垂体 - 肾上腺轴功能障碍、患者群体的易感性、感染后肠易激以及创伤后应激障碍药物治疗的副作用。