早产儿脑室周围-脑室内出血的危险因素
Risk factors of germinal matrix intraventricular hemorrhage in premature infants.
作者信息
Pekcevik Yeliz, Pasinli Aynur, Ozer Esra Arun, Erdogan Nuri
机构信息
Radiology Clinic.
Neonatalogy Clinic, Izmir Tepecik Training and Research Hospital , Izmir, Turkey.
出版信息
Iran J Pediatr. 2014 Apr;24(2):191-7.
OBJECTIVE
To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear.
METHODS
A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage, and clinical data were assessed with a checklist. Variables were analyzed by using Mann Whitney U and Fisher's exact tests and then multiple logistic regression analysis was used to evaluate the independent risk factors.
FINDINGS
Resuscitation, gestational age, hypotension, multiple birth, and birth weight were found to be independent risk factors. We determined non-linear relationship between the grades of hemorrhage and the clinical parameters. But when we classified hemorrhages as grade 1, grade 2-3 and grade 4, the relationships were found linear.
CONCLUSION
Premature infants who had resuscitation, low gestational age, hypotension, multiple birth, and low birth weight are more likely to have GM-IVH. The relationship between the clinical variables and the grades of GM-IVH does not seem to be linear.
目的
确定某些临床参数是否可用于预测出血，以及这些临床变量与出血分级之间的关系是否呈线性。
方法
回顾性分析230例孕周小于34周的早产儿。采用检查表评估生发基质-脑室内出血（GM-IVH）、出血分级及临床资料。变量分析采用Mann Whitney U检验和Fisher精确检验，然后采用多因素logistic回归分析评估独立危险因素。
结果
复苏、孕周、低血压、多胎妊娠和出生体重被发现是独立危险因素。我们确定出血分级与临床参数之间存在非线性关系。但当我们将出血分为1级、2-3级和4级时，发现这些关系呈线性。
结论
接受复苏、孕周小、低血压、多胎妊娠和出生体重低的早产儿更易发生GM-IVH。临床变量与GM-IVH分级之间的关系似乎不是线性的。
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