Tverdal A
Department of Pharmacoepidemiology, Norwegian Institute of Public Health, PO Box 4404 Nydalen, Oslo NO-0403, Norway.
Br J Cancer. 2015 Feb 3;112(3):576-9. doi: 10.1038/bjc.2014.645. Epub 2014 Dec 23.
There is insufficient epidemiological evidence on the relationship between type of coffee and the risk of prostate cancer.
The risk of prostate cancer by use of boiled vs not boiled coffee were assessed in a prospective study of 224,234 men 20-69 years. 5740 incident prostate cancers were identified.
With no coffee as reference group the hazard ratios of <1-4, 5-8 and 9+ cups per day of boiled coffee only were 0.84 (0.73-0.96), 0.80 (0.70-0.92) and 0.66 (0.55-0.80), P-trend=0.00. The corresponding figures for not boiled coffee were 0.89 (0.80-0.99), 0.91 (0.81-1.02) and 0.86 (0.74-1.00), P-trend=0.22.
An inverse relationship between number of cups per day and the risk of prostate cancer was present only for the boiled coffee type.
关于咖啡类型与前列腺癌风险之间的关系,目前尚无充分的流行病学证据。
在一项对224,234名年龄在20 - 69岁男性的前瞻性研究中,评估饮用煮咖啡与未煮咖啡患前列腺癌的风险。共识别出5740例前列腺癌新发病例。
以不喝咖啡作为参照组,每天饮用<1 - 4杯、5 - 8杯和9杯以上煮咖啡的风险比分别为0.84(0.73 - 0.96)、0.80(0.70 - 0.92)和0.66(0.55 - 0.80),P趋势 = 0.00。未煮咖啡的相应数据分别为0.89(0.80 - 0.99)、0.91(0.81 - 1.02)和0.86(0.74 - 1.00),P趋势 = 0.22。
仅煮咖啡类型呈现出每日杯数与前列腺癌风险之间的负相关关系。