Y-Hassan Shams
Department of Cardiology, Karolinska University Hospital-Huddinge , Stockholm , Sweden.
Acute Card Care. 2015 Mar;17(1):24-5. doi: 10.3109/17482941.2014.989858. Epub 2014 Dec 23.
Takotsubo syndrome (TS) is characterized by a unique pattern of transient circumferential left ventricular wall motion abnormality (LVWMA). The LVWMA in TS may be localized to the apical, mid-apical, mid-ventricular, mid-basal or basal regions of the left ventricle. Focal and generialized (global) LVWMA have also been reported. In the acute phase of TS, the hyperkinetic valve-like motion of the basal segments and/or the hyperkinetic slingshot-like motion of the apical segments combined with the firm stunned a-, hypokinetic segments result in a conspicuous left ventricular ballooning during systole. The LVWMA in TS follows most probably the local cardiac sympathetic nerve distribution and caused by local cardiac sympathetic disruption and noradrenaline spillover.
应激性心肌病（TS）的特征是左心室壁运动异常（LVWMA）呈现独特的短暂性环形模式。TS中的LVWMA可能局限于左心室的心尖、心尖中部、心室中部、基底中部或基底区域。也有局灶性和全身性（整体）LVWMA的报道。在TS的急性期，基底节段的高动力瓣膜样运动和/或心尖节段的高动力弹弓样运动与僵硬的顿抑a节段、运动减弱节段相结合，导致收缩期左心室明显膨出。TS中的LVWMA很可能遵循局部心脏交感神经分布，由局部心脏交感神经破坏和去甲肾上腺素溢出引起。
