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[寒冷压迫后未进行复温时生物体呼吸功能的恢复]

[Restoration of respiratory function of an organism after cold oppressions without warming].

作者信息

Arokina N K, Ivanov K P

出版信息

Patol Fiziol Eksp Ter. 2014 Jul-Sep(3):32-6.

PMID:25536788
Abstract

In experiments on rats studied influence of intravenous introduction NazdTA on respiratory function of rats after the full termination of breath at deep hypothermia. It is shown that such method without warming application it is possible to lower on 1.5-2.0 degrees C a temperature threshold of approach full a cold paralysis of respiratory function of an organism. It confirms the hypothesis put forward earlier about an important role of infringement of balance of ions of calcium in cytoplasm of cells in development of a pathology of an organism at deep hypothermia. The received results can be used at resuscitation of victims accidental hypothermia.

摘要

在对大鼠的实验中,研究了静脉注射依地酸钠(NazdTA)对大鼠在深度低温下呼吸完全停止后呼吸功能的影响。结果表明,在不进行复温的情况下,这种方法可以将机体呼吸功能完全冷麻痹的温度阈值降低1.5 - 2.0摄氏度。这证实了先前提出的关于细胞胞质中钙离子平衡失调在深度低温下机体病理发展中起重要作用的假设。所获得的结果可用于意外低温受害者的复苏。

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