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结构相关的exbB和tolQ基因在赋予对tonB依赖性大肠杆菌素、噬菌体和白霉素敏感性方面是可互换的。

The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity.

作者信息

Braun V

机构信息

Mikrobiologie II, Universität Tübingen, Federal Republic of Germany.

出版信息

J Bacteriol. 1989 Nov;171(11):6387-90. doi: 10.1128/jb.171.11.6387-6390.1989.

Abstract

Double exbB tolQ mutants of Escherichia coli were completely resistant to bacteriophages T1 and phi 80, in contrast to strains with exbB or tolQ mutations, which were sensitive. Cells carrying mutations in exbB were partially tolerant to colicins B, D, and M and became fully tolerant by the introduction of tolQ mutations. This suggested involvement of both exbB and tolQ in tonB-dependent uptake.

摘要

与具有exbB或tolQ突变且敏感的菌株相比,大肠杆菌的双exbB tolQ突变体对噬菌体T1和phi 80完全耐药。携带exbB突变的细胞对大肠菌素B、D和M有部分耐受性,通过引入tolQ突变后变得完全耐受。这表明exbB和tolQ都参与了tonB依赖性摄取。

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